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Merck

CNTF

ciliary neurotrophic factor

Synonymes:
HCNTF
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(1270) Summary: The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of the upstream ZFP91 gene and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse. [provided by RefSeq, Oct 2010]
  • Mouse(12803) ciliary neurotrophic factor
  • Rat(25707) ciliary neurotrophic factor
  • domestic cat(101097592) ciliary neurotrophic factor
  • chicken(396488) ciliary neurotrophic factor
  • Domestic Rabbit(100009117) ciliary neurotrophic factor
  • domestic guinea pig(100724905) ciliary neurotrophic factor
  • naked mole-rat(101713822) ciliary neurotrophic factor
  • dog(483464) ciliary neurotrophic factor
  • cow(100848228) ciliary neurotrophic factor

Custom & Knockdown Gene Products

ELISA

Numéro du produit
Description
Espèce(s)
Human CNTF ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Espèce(s)
human
Rat CNTF ELISA Kit, for serum, plasma and cell culture supernatant,
Espèce(s)
mouse

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anti-CNTF antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution, Ab1,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-Ciliary Neurotrophic Factor Antibody, clone 4-68, clone 4-68, Chemicon®, from mouse,
Espèces réactives
human, monkey, mouse, rat
Application
immunohistochemistry
western blot
Anti-CNTF antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
western blot

Proteins

Numéro du produit
Description
Espèce(s)
Ciliary Neurotrophic Factor human, CNTF, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture,
Espèce(s)
human
CNTF, recombinant, ,
Espèce(s)
rat

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human CNTF,
Espèce(s)
human
MISSION® esiRNA, targeting human ZFP91, ZFP91-CNTF,
Espèce(s)
human