KAT6B
K(lysine) acetyltransferase 6B
Synonymes:
GTPTS, MORF, MOZ2, MYST4, ZC2HC6B, qkf, querkopf
Espèce(s):
Human KAT6B (23522), Mouse Kat6b (54169), dog KAT6B (479254), Zebrafish kat6b (568932), chicken KAT6B (423734), naked mole-rat Kat6b (101720761), domestic cat KAT6B (101090801), cow KAT6B (535403), sheep KAT6B (101123266), domestic guinea pig Kat6b (100723383)
ID UniProtKB:
ID du gène:
- Human(23522) Summary: The protein encoded by this gene is a histone acetyltransferase and component of the MOZ/MORF protein complex. In addition to its acetyltransferase activity, the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end. This protein is necessary for RUNX2-dependent transcriptional activation and could be involved in brain development. Mutations have been found in patients with genitopatellar syndrome. A translocation of this gene and the CREBBP gene results in acute myeloid leukemias. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012]
- Mouse(54169) K(lysine) acetyltransferase 6B
- dog(479254) K(lysine) acetyltransferase 6B
- Zebrafish(568932) K(lysine) acetyltransferase 6B
- chicken(423734) K(lysine) acetyltransferase 6B
- naked mole-rat(101720761) K(lysine) acetyltransferase 6B
- domestic cat(101090801) K(lysine) acetyltransferase 6B
- cow(535403) K(lysine) acetyltransferase 6B
- sheep(101123266) K(lysine) acetyltransferase 6B
- domestic guinea pig(100723383) K(lysine) acetyltransferase 6B
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