NAT2
N-acetyltransferase 2 (arylamine N-acetyltransferase)
Synonymes:
AAC2, NAT-2, PNAT
Espèce(s):
Human NAT2 (10), Mouse Nat2 (17961), Rat Nat2 (116632), Domestic Rabbit NAT2 (100008974), chicken NAT2 (770256)
ID UniProtKB:
ID du gène:
- Human(10) Summary: This gene encodes an enzyme that functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are responsible for the N-acetylation polymorphism in which human populations segregate into rapid, intermediate, and slow acetylator phenotypes. Polymorphisms in this gene are also associated with higher incidences of cancer and drug toxicity. A second arylamine N-acetyltransferase gene (NAT1) is located near this gene (NAT2). [provided by RefSeq, Jul 2008]
- Mouse(17961) N-acetyltransferase 2 (arylamine N-acetyltransferase)
- Rat(116632) N-acetyltransferase 2
- Domestic Rabbit(100008974) N-acetyltransferase 2 (arylamine N-acetyltransferase)
- chicken(770256) N-acetyltransferase 2 (arylamine N-acetyltransferase)
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