TP63
tumor protein p63
Synonymes:
AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L
Espèce(s):
Human TP63 (8626), Rat Tp63 (246334), Zebrafish tp63 (260407), chicken TP63 (374269), dog TP63 (488125), domestic cat TP63 (101095124), domestic guinea pig Tp63 (100732143), Horse TP63 (100059752), sheep TP63 (101108874), sheep TP63 (100048992) ...Plus
ID UniProtKB:
ID du gène:
- Human(8626) Summary: This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined. [provided by RefSeq, Jul 2008]
- Rat(246334) tumor protein p63
- Zebrafish(260407) tumor protein p63
- chicken(374269) tumor protein p63
- dog(488125) tumor protein p63
- domestic cat(101095124) tumor protein p63
- domestic guinea pig(100732143) tumor protein p63
- Horse(100059752) tumor protein p63
- sheep(101108874) tumor protein p63
- sheep(100048992) tumor protein p63
- naked mole-rat(101710600) tumor protein p63
- cow(615335) tumor protein p63
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Antibodies
Numéro du produit
Description
Espèces réactives
Application
Anti-p40 Antibody, from rabbit, purified by affinity chromatography,
Espèces réactives
human, mouse
Application
immunohistochemistry
western blot
western blot
Anti-p63 (Tumor Protein 63) Rabbit Monoclonal Antibody, clone RM383, affinity purified immunoglobulin,
Espèces réactives
human
Application
immunohistochemistry
western blot
western blot
Anti-P40 (TP63) Antibody, clone 11H1, clone 11H1, from mouse,
Espèces réactives
human
Application
western blot
Anti-p40 (deltaNp63) Rabbit Monoclonal Antibody, clone RM392, affinity purified immunoglobulin,
Espèces réactives
human
Application
immunohistochemistry
Monoclonal Anti-TP63 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL3748, purified immunoglobulin, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
western blot
western blot
Proteins
Numéro du produit
Description
Espèce(s)
p63, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human
esiRNA
Numéro du produit
Description
Espèce(s)