Merck
All Photos(1)

15369

Sigma-Aldrich

N-Boc-ethylenediamine

≥98.0% (NT)

Synonym(s):
N-Boc-1,2-diaminoethane, tert-Butyl N-(2-aminoethyl)carbamate
Linear Formula:
(CH3)3COCONHCH2CH2NH2
CAS Number:
Molecular Weight:
160.21
Beilstein:
1932330
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

≥98.0% (NT)

reaction suitability

reagent type: cross-linking reagent
reagent type: spacer

refractive index

n20/D 1.458 (lit.)
n20/D 1.458

bp

72-80 °C/0.1 mmHg (lit.)

density

1.012 g/mL at 20 °C (lit.)

SMILES string

NCCNC(OC(C)(C)C)=O

InChI

1S/C7H16N2O2/c1-7(2,3)11-6(10)9-5-4-8/h4-5,8H2,1-3H3,(H,9,10)

Inchi Key

AOCSUUGBCMTKJH-UHFFFAOYSA-N

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Packaging

1, 5, 25 g in glass bottle

Other Notes

Mono-protected derivative of ethylenediamine, preparation of pharmacologically active analogues; introduction of an ethylenediamine spacer.

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Skin Corr. 1B

Storage Class Code

8A - Combustible, corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

Synthesis of N,N-dilactitol ethylenediamine: a versatile spacer for attachment of residualizing labels to protein.
M M Dowd et al.
Analytical biochemistry, 205(2), 369-371 (1992-09-01)
W S Saari et al.
Journal of medicinal chemistry, 34(10), 3132-3138 (1991-10-01)
Basic nitrobenzenesulfonamides containing nitroisopropyl and (ureidooxy)methyl groups were prepared and evaluated as novel hypoxic cell selective cytotoxic agents. In vitro, N-(2-aminoethyl)-N-methyl-3-nitro-4-(1-methyl-1-nitroethyl)benzene sulfonamide hydrochloride (11) proved to be preferentially toxic to hypoxic EMT6 mammary carcinoma cells. At 1 mM concentration in
E Morier-Teissier et al.
Journal of medicinal chemistry, 36(15), 2084-2090 (1993-07-23)
A new molecule 4 [(GGH-DAE)2DHQ] associating the 1,4,5,8-tetrahydroxyanthraquinone ring (DHQ) of the antitumor drug mitoxantrone (2), two diaminoethylene chains (DAE), and the metal-chelating peptide Gly-Gly-His (GGH) has been synthesized. Such a molecule presents characteristics able to induce antitumor activity: compound
Hao Li et al.
Investigative ophthalmology & visual science, 58(12), 5142-5150 (2017-10-08)
Intravitreal injection of antiangiogenic agents is becoming a standard treatment for neovascular retinal diseases. Sustained release of therapeutics by injecting colloidal carriers is a promising approach to reduce the injection frequency, which reduces treatment burdens and the risk of complications
Qi Zhang et al.
Journal of biophotonics, 11(6), e201700339-e201700339 (2018-01-18)
Targeting cyclooxygenase-2 (COX-2) for molecular imaging is an attractive approach applicable for its overexpression in inflammation and many malignancies. Herein, for monitoring COX-2, we synthesize a specific COX-2 probe celecoxib-MPA probe (CMP), based on celecoxib and a water-soluble near-infrared dye

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