Merck
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746223

Sigma-Aldrich

Maleimide-PEG2-succinimidyl ester

≥95%

Synonym(s):
Maleimide-PEG2-NHS, 3-[2-[2-[[3-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]ethoxy]ethoxy]propanoic acid 2,5-dioxo-1-pyrrolidinyl ester
Empirical Formula (Hill Notation):
C18H23N3O9
CAS Number:
Molecular Weight:
425.39
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

≥95%

form

solid

reaction suitability

reaction type: Pegylations
reagent type: cross-linking reagent

mp

92-94 °C

storage temp.

−20°C

SMILES string

O=C(N1CCC(NCCOCCOCCC(ON(C(CC2)=O)C2=O)=O)=O)C=CC1=O

InChI

1S/C18H23N3O9/c22-13(5-8-20-14(23)1-2-15(20)24)19-7-10-29-12-11-28-9-6-18(27)30-21-16(25)3-4-17(21)26/h1-2H,3-12H2,(H,19,22)

InChI key

TZPDZOJURBVWHS-UHFFFAOYSA-N

Related Categories

Application

Heterobifunctional crosslinker with short ethylene oxide spacer for linking amine- to sulfhydryl-containing compounds or biomolecules. Maleimide functional group will react with sulfhydryls and the succinimidyl ester group will react with amines. Spacer length is 17.6 angstroms.

Packaging

50, 250 mg in amber glass bottle

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

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More Documents

Quotes and Ordering

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Sinem K Saka et al.
Nature biotechnology, 37(9), 1080-1090 (2019-08-21)
Spatial mapping of proteins in tissues is hindered by limitations in multiplexing, sensitivity and throughput. Here we report immunostaining with signal amplification by exchange reaction (Immuno-SABER), which achieves highly multiplexed signal amplification via DNA-barcoded antibodies and orthogonal DNA concatemers generated
Florian Schueder et al.
Nature communications, 8(1), 2090-2090 (2017-12-14)
Single-molecule localization microscopy (SMLM) can visualize biological targets on the nanoscale, but complex hardware is required to perform SMLM in thick samples. Here, we combine 3D DNA points accumulation for imaging in nanoscale topography (DNA-PAINT) with spinning disk confocal (SDC)
Nirakar Basnet et al.
Nature cell biology, 20(10), 1172-1180 (2018-09-27)
Microtubules are central elements of the eukaryotic cytoskeleton that often function as part of branched networks. Current models for branching include nucleation of new microtubules from severed microtubule seeds or from γ-tubulin recruited to the side of a pre-existing microtubule.
Thomas Schlichthaerle et al.
Chembiochem : a European journal of chemical biology, 20(8), 1032-1038 (2018-12-28)
Current optical super-resolution implementations are capable of resolving features spaced just a few nanometers apart. However, translating this spatial resolution to cellular targets is limited by the large size of traditionally employed primary and secondary antibody reagents. Recent advancements in

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