Merck
  • 80822
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80822

Supelco

(S)-Naproxen methyl ester

pharmaceutical impurity standard

Synonym(s):
Naproxen Impurity E (PhEur), (2S)-2-(6-Methoxy-2-naphthyl)propionic acid methyl ester, Methyl (αS)-6-methoxy-α-methyl-2-naphthaleneacetate, Methyl (2S)-2-(6-methoxynaphthalen-2-yl)propanoate
Empirical Formula (Hill Notation):
C15H16O3
CAS Number:
Molecular Weight:
244.29
Beilstein:
4352971
MDL number:
PubChem Substance ID:
NACRES:
NA.24

Quality Level

Assay

≥98.0% (HPLC)

optical activity

[α]/D 72.0 to 84.0°, c = 0.1 in chloroform

shelf life

limited shelf life, expiry date on the label

impurities

≤0.5% water

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

C[C@H](C(OC)=O)C1=CC2=CC=C(OC)C=C2C=C1

InChI

1S/C15H16O3/c1-10(15(16)18-3)11-4-5-13-9-14(17-2)7-6-12(13)8-11/h4-10H,1-3H3/t10-/m0/s1

InChI key

ZFYFBPCRUQZGJE-JTQLQIEISA-N

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(S)-Naproxen methyl ester pharmaceutical impurity standard

Supelco

80822

(S)-Naproxen methyl ester

(S)-Trolox methyl ether for chiral derivatization, LiChropur™, ≥98.0%

Supelco

93510

(S)-Trolox methyl ether

assay

≥98.0% (HPLC)

assay

98%

assay

≥98.0% (sum of enantiomers, HPLC)

assay

97%

shelf life

limited shelf life, expiry date on the label

shelf life

-

shelf life

-

shelf life

-

application(s)

pharmaceutical (small molecule)

application(s)

-

application(s)

-

application(s)

-

format

neat

format

-

format

-

format

-

storage temp.

2-8°C

storage temp.

-

storage temp.

-

storage temp.

-

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

General description

(S)-Naproxen methyl ester is an ester of the non-steroidal, anti-inflammatory drug, (S)-naproxen

Signal Word

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

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