C1389

Carbenicillin disodium salt

89.0-100.5% anhydrous basis

• Synonym(s): Carbenicillin, α-Carboxybenzylpenicillin disodium salt
• Empirical Formula (Hill Notation): C₁₇H₁₆N₂Na₂O₆S
• CAS Number: 4800-94-6
• Molecular Weight: 422.36
• Beilstein: 5722128
• EC Number: 225-360-8
• MDL number: MFCD00077683
• PubChem Substance ID: 24892409
• NACRES: NA.76

Properties

• Quality Level: 200
• Assay: 89.0-100.5% anhydrous basis
• form: powder
• solubility: H₂O: 50 mg/mL
• antibiotic activity spectrum: Gram-negative bacteria; Gram-positive bacteria
• Mode of action: cell wall synthesis | interferes
• storage temp.: 2-8°C
• SMILES string: [Na+].[Na+].CC1(C)S[C@@H]2[C@H](NC(=O)C(C([O-])=O)c3ccccc3)C(=O)N2[C@H]1C([O-])=O
• InChI: 1S/C17H18N2O6S.2Na/c1-17(2)11(16(24)25)19-13(21)10(14(19)26-17)18-12(20)9(15(22)23)8-6-4-3-5-7-8;;/h3-7,9-11,14H,1-2H3,(H,18,20)(H,22,23)(H,24,25);;/q;2*+1/p-2/t9?,10-,11+,14-;;/m1../s1
• InChI key: RTYJTGSCYUUYAL-YCAHSCEMSA-L

Description

General description

Chemical structure: peptide

Application

Used for selection of ampr transformed cells and to study the role of penicillin-sensitive transpeptidases in cell wall biosynthesis.

Biochem/physiol Actions

Carboxypenicillin antibiotic that inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Analog to ampicillin.
Antimicrobial spectrum: Gram-positive and Gram-negative bacteria, Pseudomonas.

Analysis Note

Stable at 37 °C for 3 days

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

Safety Information

• Pictograms: GHS08
• Signal Word: Danger
• Hazard Statements: H317 - H334
• Precautionary Statements: P261 - P272 - P280 - P284 - P302 + P352 - P333 + P313
• Hazard Classifications: Resp. Sens. 1 - Skin Sens. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves