53048

5-Carboxy-tetramethylrhodamine N-succinimidyl ester

BioReagent, suitable for fluorescence

• Synonym(s): "4-Carboxytetramethylrhodamine N-succinimidyl ester", 5-TAMRA
• Empirical Formula (Hill Notation): C₂₉H₂₅N₃O₇
• CAS Number: 150810-68-7
• Molecular Weight: 527.52
• MDL number: MFCD03453223
• PubChem Substance ID: 57651396
• NACRES: NA.32

Properties

• product line: BioReagent
• Quality Level: 100
• solubility: DMF: soluble; acetonitrile: soluble
• fluorescence: λ_ex 543 nm; λ_em 578 nm in 0.1 M phosphate pH 7.0
• suitability: suitable for fluorescence
• storage temp.: −20°C
• SMILES string: CN(C)c1ccc2c(OC3=C\C(C=CC3=C2c4ccc(cc4C([O-])=O)C(=O)ON5C(=O)CCC5=O)=[N+](\C)C)c1
• InChI: 1S/C29H25N3O7/c1-30(2)17-6-9-20-23(14-17)38-24-15-18(31(3)4)7-10-21(24)27(20)19-8-5-16(13-22(19)28(35)36)29(37)39-32-25(33)11-12-26(32)34/h5-10,13-15H,11-12H2,1-4H3
• InChI key: VWFRSNKRTNUMET-UHFFFAOYSA-N

Description

Application

5-Carboxy-tetramethylrhodamine N-succinimidyl ester (5-TAMRA) is used as an amine coupling reagent to form 5-carboxy-tetramethylrhodamine (5-TAMRA) derivatized compounds. 5-TAMRA derivatized compounds may be used in applications as enzyme substrates, molecular probes, molecular beacons and as fluorescence resonance energy transfer (FRET) partners.

Other Notes

Fluorescent labeling of DNA and RNA

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves