F5135

N-[3-(2-Furyl)acryloyl]-Leu-Gly-Pro-Ala

• Synonym(s): FALGPA, N-[3-(2-Furyl)acryloyl]-L-leucyl-glycyl-L-prolyl-L-alanine
• Empirical Formula (Hill Notation): C₂₃H₃₂N₄O₇
• CAS Number: 78832-65-2
• Molecular Weight: 476.52
• MDL number: MFCD00133552
• PubChem Substance ID: 329799652
• NACRES: NA.32

Properties

• Quality Level: 200
• UniProt accession no.: Q02111
• storage temp.: −20°C
• SMILES string: CC(C)C[C@H](NC(=O)\C=C\c1ccco1)C(=O)NCC(=O)N2CCC[C@H]2C(=O)N[C@@H](C)C(O)=O
• InChI: 1S/C23H32N4O7/c1-14(2)12-17(26-19(28)9-8-16-6-5-11-34-16)21(30)24-13-20(29)27-10-4-7-18(27)22(31)25-15(3)23(32)33/h5-6,8-9,11,14-15,17-18H,4,7,10,12-13H2,1-3H3,(H,24,30)(H,25,31)(H,26,28)(H,32,33)/b9-8+/t15-,17-,18-/m0/s1
• InChI key: ZLFQNOJSYZSINX-PVJKAEHXSA-N
• Gene Information: mouse ... Prkcq(18761)

Description

Amino Acid Sequence

FA-Leu-Gly-Pro-Ala

General description

N-[3-(2-Furyl)acryloyl]-Leu-Gly-Pro-Ala or FALGPA is a synthetic substance which resemble the primary structure of collagen, and is hydrolyzed by all known collagenases.

Application

N-[3-(2-Furyl)acryloyl]-Leu-Gly-Pro-Ala has been used for use in FALGPA assay performed using GBS (Group B Streptococci) USF704.

Packaging

5, 25, 50, 100 mg

Bottomless glass bottle. Contents are inside inserted fused cone.

Biochem/physiol Actions

N-[3-(2-Furyl)acryloyl]-Leu-Gly-Pro-Ala or FALGPA is hydrolyzed by collagenases and the optimum pH for hydrolysis is 7.4.

Substrates

Substrate for collagenase.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves