Merck
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G5146

Sigma-Aldrich

D-(+)-Glucose

Hybri-Max, powder, BioReagent, suitable for hybridoma

Synonym(s):
Dextrose
Empirical Formula (Hill Notation):
C6H12O6
CAS Number:
Molecular Weight:
180.16
Beilstein:
1724615
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.75

biological source

maize

Quality Level

grade

Hybri-Max

product line

BioReagent

Assay

≥99.5%

form

powder

technique(s)

cell culture | hybridoma: suitable

impurities

endotoxin, tested

mp

150-152 °C (lit.)

solubility

H2O: 2g + 15 mL (Tested)

SMILES string

OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1

InChI key

WQZGKKKJIJFFOK-DVKNGEFBSA-N

Gene Information

human ... PYGM(5837)

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This Item
49139G7528G7021
D-(+)-Glucose Hybri-Max™, powder, BioReagent, suitable for hybridoma

Sigma-Aldrich

G5146

D-(+)-Glucose

D-(+)-Glucose BioUltra, anhydrous, ≥99.5% (sum of enantiomers, HPLC)

Sigma-Aldrich

49139

D-(+)-Glucose

D-(+)-Glucose BioXtra, ≥99.5% (GC)

Sigma-Aldrich

G7528

D-(+)-Glucose

D-(+)-Glucose powder, BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture, ≥99.5%

Sigma-Aldrich

G7021

D-(+)-Glucose

biological source

maize

biological source

-

biological source

maize

biological source

-

grade

Hybri-Max

grade

anhydrous

grade

-

grade

-

product line

BioReagent

product line

BioUltra

product line

BioXtra

product line

BioReagent

assay

≥99.5%

assay

≥99.5% (sum of enantiomers, HPLC)

assay

≥99.5% (GC)

assay

≥99.5%

form

powder

form

powder

form

powder

form

powder

technique(s)

cell culture | hybridoma: suitable

technique(s)

-

technique(s)

gas chromatography (GC): suitable

technique(s)

cell culture | insect: suitable, cell culture | mammalian: suitable, cell culture | plant: suitable

General description

Glycogen phosphorylase (PYG) exists as brain and muscle isoform. It is expressed in astrocytes and neurons respectively. The PYGM gene is mapped to human chromosome 11q13.1.

Application

D-(+)-Glucose has been used in cell engineering. It has also been used to perform oral glucose tolerance test.

Biochem/physiol Actions

Glycogen phosphorylase, muscle associated (PYGM), is an important contributor to glycogenolysis. Down regulation of PYGM gene is observed in schizophrenia. Mutation in PYGM leads to McArdle disease, a glycogen storage disorder. The PYGM gene is significantly associated with energy production.

Preparation Note

The material may produce a yellowish solution if prepared at a higher concentration than 2g + 15ml.

Legal Information

Hybri-Max is a trademark of Sigma-Aldrich Co. LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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