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Luis Claudio Cacciatore et al.
Aquatic toxicology (Amsterdam, Netherlands), 128-129, 124-134 (2013-01-08)
Though pesticide mixtures are commonly encountered in fresh water systems, the knowledge of their effects on non-target aquatic species is scarce. The present investigation was undertaken to explore the in vivo inhibition of the freshwater gastropod snail Planorbarius corneus cholinesterase
Qinghai Wang et al.
Water science and technology : a journal of the International Association on Water Pollution Research, 67(9), 1908-1915 (2013-05-10)
For understanding the influence of initial concentrations of pesticides in the water body on removal efficiency of the contaminant by aquatic plants, one hydroponics experiment was used to investigate the influence of initial concentration (1-16 mg L(-1)) on toxicity and
Wen Li et al.
Journal of applied toxicology : JAT, 33(10), 1187-1191 (2012-05-23)
The blood-brain barrier (BBB) is formed by specialized endothelial cells lining capillaries in the central nervous system (CNS). We previously demonstrated that exposure to very low concentrations of the organophosphorus insecticide chlorpyrifos (CPF) decreased electrical resistance across the BBB in
Kamil Musilek et al.
Bioorganic & medicinal chemistry letters, 16(3), 622-627 (2005-11-18)
Six potential AChE reactivators were synthesized using modification of currently known synthetic pathways. Their potency to reactivate AChE inhibited by insecticide chlorpyrifos was tested in vitro. According to the results, (E)-1-(2-hydroxyiminomethylpyridinium)-4-(4-hydroxyiminomethylpyridinium)-but-2-ene dibromide seems to be the most potent AChE reactivator.
Theruvakkattil Sreenivasan Sreeprasad et al.
Journal of hazardous materials, 246-247, 213-220 (2013-01-15)
An in situ strategy for the preparation of graphene immobilized on sand using asphalt, a cheap carbon precursor is presented. The as-synthesized material was characterized in detail using various spectroscopic and microscopic techniques. The presence of G and D bands
G R Oliver et al.
Neurotoxicology, 21(1-2), 203-208 (2000-05-04)
FQPA requires determination of the combined potential risk from both dietary (food and drinking water) and non-dietary (residential) routes of exposures to pesticides. Critical to the implementation and ultimately to the impact of FQPA are the validity of the risk
Sumitra Arora et al.
Environmental monitoring and assessment, 186(1), 361-366 (2013-09-03)
The integrated pest management (IPM) modules of pesticide schedule on Basmati rice were validated at field experiments conducted in Northern India for consecutive 3 years (2005-2008). The pesticide residues were found below the detectable limit (<0.01-0.001 mg/kg) in soil and irrigation water
Mansur A Sandhu et al.
The Journal of toxicological sciences, 38(2), 237-244 (2013-03-29)
The oral intubation of chlorpyrifos, an extensively used organophosphate insecticide, was tested for its capability to induce in vivo genotoxic upshot in blood lymphocytes of 24 male and female Wistar rats using biomarker of genotoxicity. Rats were orally administered with
W Guo et al.
Journal of economic entomology, 106(3), 1112-1117 (2013-07-20)
The efficacy of entomopathogenic nematodes (EPNs) against the white grub Holotrichia parallela Motschulsky (Coleoptera: Scarabaeidae) in the peanut (Arachis hypogaea L.) fields was evaluated. In the first experiment with a high initial white grub population (24.65 +/- 2.44 larvae per
Theodore A Slotkin et al.
Environmental toxicology and pharmacology, 36(2), 284-287 (2013-05-21)
Although organophosphate pesticides are not usually characterized as "endocrine disruptors," recent work points to potential, long-term reductions of circulating thyroid hormones after developmental exposures to chlorpyrifos that are devoid of observable toxicity. We administered chlorpyrifos to developing rats on gestational
D J Clegg et al.
Journal of toxicology and environmental health. Part B, Critical reviews, 2(3), 257-279 (1999-08-03)
A panel of toxicology and medical experts was convened on 7-9 April 1997 to consider the available scientific literature on chlorpyrifos, both published and unpublished, to determine the acute and chronic toxicology reference dose (RfD). In the course of reviewing
C A Moore et al.
Toxicology letters, 229(1), 66-72 (2014-06-10)
To date, there has been little research investigating low-level human exposure to chemicals, and so the aim of this study was to examine the percutaneous penetration of organophosphates (dichlorvos and chlorpyrifos) using low-level exposure scenarios in vitro. Dermal absorption of
Constantin Mircioiu et al.
Toxicology letters, 219(2), 99-106 (2013-03-23)
Chemical warfare agents, such as soman, and pesticides, such as chlorpyrifos, dichlorvos or malathion, are toxic organophosphorous compounds (OPCs) that are readily absorbed by the skin. Decontamination using solvents or surfactants may modify the cornified layer - the skin's main
Qiyu Zhao et al.
Regulatory toxicology and pharmacology : RTP, 44(2), 111-124 (2005-12-20)
Chlorpyrifos is an inhibitor of cholinesterase (ChE) and inhibition of ChE is believed to be the most sensitive effect in all animal species evaluated and in humans from previous evaluations. Recent literature, in particular epidemiology studies reporting associations between chlorpyrifos
Marina Schäfer et al.
Chemico-biological interactions, 206(3), 472-478 (2013-09-03)
Organophosphourus compounds (OPC, including nerve agents and pesticides) exhibit acute toxicity by inhibition of acetylcholinesterase. Lung affections are frequent complications and a risk factor for death. In addition, epidemiological studies reported immunological alterations after OPC exposure. In our experiments we
Motohiro Tomizawa et al.
Journal of medicinal chemistry, 51(14), 4213-4218 (2008-06-24)
Neonicotinoid agonists with a nitroimino or cyanoimino pharmacophore are the newest of the four most important classes of insecticides. Our studies on the nicotinic receptor structure in the neonicotinoid-bound state revealed a unique niche of about 6 A depth beyond
Robert U Svensson et al.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 32(1), 29-39 (2013-06-14)
Environmental factors are likely to interact with genetic determinants to influence prostate cancer progression. The Agricultural Health Study has identified an association between exposure to organophosphorous pesticides including chlorpyrifos, and increased prostate cancer risk in pesticide applicators with a first-degree
George N Mbata et al.
Journal of economic entomology, 106(5), 2072-2076 (2013-11-15)
The peanut burrower bug, Pangaeus bilineatus (Say), is an important pest of peanut (Arachis hypogaea L.) in the southern United States. Current control methods for this pest, which are based on the use of chemical insecticides, have not been successful.
Jing Liu et al.
Toxicology and applied pharmacology, 272(3), 608-615 (2013-08-13)
Parathion (PS) and chlorpyrifos (CPF) are organophosphorus insecticides (OPs) that elicit acute toxicity by inhibiting acetylcholinesterase (AChE). Endocannabinoids (eCBs, N-arachidonoylethanolamine, AEA; 2-arachidonoylglycerol, 2AG) can modulate neurotransmission by inhibiting neurotransmitter release. We proposed that differential inhibition of eCB-degrading enzymes (fatty acid
G Chiapella et al.
Placenta, 34(9), 792-798 (2013-07-16)
Reactive oxygen species (ROS) are produced by a number of physiological and pathological processes which influence the function of a diverse array of cellular events. An imbalance between ROS generation and elimination was reported for different environmental xenobiotics exposure. Here
Dhirendra Nath Barman et al.
Ecotoxicology and environmental safety, 108, 135-141 (2014-07-26)
Chlorpyrifos is an organophosphate pesticide that has adverse effect on animals and plants. We isolated endophytic bacterial strain, Pseudomonas sp. BF1-3, from balloon flower root which can hydrolyze chlorpyrifos. A gene (ophB) encoding a protein involved in chlorpyrifos degradation from
Abby A Li et al.
Journal of toxicology and environmental health. Part B, Critical reviews, 15(2), 109-184 (2012-03-10)
Developmental neurobehavioral outcomes attributed to exposure to chlorpyrifos (CPF) obtained from epidemiologic and animal studies published before June 2010 were reviewed for risk assessment purposes. For epidemiological studies, this review considered (1) overall strength of study design, (2) specificity of
Daland R Juberg et al.
Regulatory toxicology and pharmacology : RTP, 66(3), 249-263 (2013-03-26)
Chlorpyrifos was selected for EPA's Endocrine Disruptor Screening Program (EDSP) based on widespread use and potential for human and environmental exposures. The purpose of the program is to screen chemicals for their potential to interact with the estrogen, androgen, or
J V Peter et al.
Clinical toxicology (Philadelphia, Pa.), 51(9), 850-854 (2013-09-27)
Clinical scoring systems are used to predict mortality rate in hospitalized patients. Their utility in organophosphate (OP) poisoning has not been well studied. In this retrospective study of 396 patients, we evaluated the performance of the Acute Physiology and Chronic
Anupama Ojha et al.
Environmental toxicology, 28(10), 543-552 (2011-07-26)
Organophosphate pesticides are among the most widely used synthetic chemicals for controlling a wide variety of pests. Chlorpyrifos (CPF), methyl parathion (MPT), and malathion (MLT) are among the most extensively used organophosphate (OP) pesticides. The main target of action of
Jae Hyeon Park et al.
Toxicology and applied pharmacology, 268(1), 55-67 (2013-01-29)
Recent studies have shown that up-regulation of autophagy may be a tractable therapeutic intervention for clearing disease-causing proteins, including α-synuclein, ubiquitin, and other misfolded or aggregated proteins in pesticide-induced neurodegeneration. In a previous study, we reported that chlorpyrifos (CPF)-induced mitochondria-dependent
Caridad López-Granero et al.
Toxicology, 308, 41-49 (2013-04-03)
Chlorpyrifos (CPF) is an organophosphate (OP) insecticide that is metabolically activated to the highly toxic chlorpyrifos oxon. Dietary exposure is the main route of intoxication for non-occupational exposures. However, only limited behavioral effects of chronic dietary exposure have been investigated.
Chlorpyrifos: ecological risk assessment in North American aquatic environments.
J P Giesy et al.
Reviews of environmental contamination and toxicology, 160, 1-129 (2006-06-29)
Lizanne Janssens et al.
Environmental pollution (Barking, Essex : 1987), 177, 143-149 (2013-03-19)
While there is increasing concern that pesticide stress can interact with stress imposed by antagonistic species including pathogens, it is unknown whether this also holds for non-pathogenic bacteria. We exposed Enallagma cyathigerum damselfly larvae to the pesticide chlorpyrifos and a
J W Albers et al.
Journal of toxicology and environmental health. Part B, Critical reviews, 2(4), 301-324 (1999-12-22)
This report summarizes the deliberations of an eight-member panel of scientists convened by Dow AgroSciences in cooperation with the U.S. Environmental Protection Agency (EPA). The panel was charged with evaluating the scientific literature on the health effects potentially associated with
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