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J Von Der Wellen et al.
Clinical toxicology (Philadelphia, Pa.), 51(10), 918-922 (2013-11-10)
Numerous studies demonstrated a limited efficacy of clinically used oximes in case of poisoning by various organophosphorus compounds. A broad spectrum oxime antidote covering all organophosphorus nerve agents and pesticides is still missing and effective (bio-)scavengers have not yet been
Ali Abdel-Rahman et al.
Journal of toxicology and environmental health. Part A, 67(4), 331-356 (2004-01-10)
Malathion (O,O-dimethyl-S-[1,2-carbethoxyethyl]phosphorodithionate), DEET (N,N-diethyl-m-toluamide), and permethrin [(+/-)-cis/trans-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane carboxylic acid (3-phenoxyphenyl) methyl ester] are commonly used pesticides. To determine the effects of the dermal application of these chemicals, alone or in combination, the sensorimotor behavior, central cholinergic system, and histopathological alterations
Alice S M Tidman et al.
The Practitioner, 257(1761), 23-27 (2013-07-03)
Scabies is caused by infestation with a parasitic mite Sarcoptes scabiei var hominis. The itch and rash appear to be largely the result of a delayed (type IV) allergic reaction to the mite, its eggs and excreta. Scabies is spread
Maya L Groner et al.
Ecological applications : a publication of the Ecological Society of America, 23(6), 1443-1454 (2013-10-24)
For the past several decades, amphibian populations have been decreasing around the globe at an unprecedented rate. Batrachochytrium dendrobatidis (Bd), the fungal pathogen that causes chytridiomycosis in amphibians, is contributing to amphibian declines. Natural and anthropogenic environmental factors are hypothesized
S Abdul Majeed et al.
Cell biology and toxicology, 29(1), 59-73 (2012-12-12)
Rohu gill cell line (LRG) was established from gill tissue of Indian major carp (Labeo rohita), a freshwater fish cultivated in India. The cell line was maintained in Leibovitz's L-15 supplemented with 10 % foetal bovine serum (FBS). This cell line
Constantin Mircioiu et al.
Toxicology letters, 219(2), 99-106 (2013-03-23)
Chemical warfare agents, such as soman, and pesticides, such as chlorpyrifos, dichlorvos or malathion, are toxic organophosphorous compounds (OPCs) that are readily absorbed by the skin. Decontamination using solvents or surfactants may modify the cornified layer - the skin's main
Guang-Mao Shen et al.
Pest management science, 68(12), 1553-1563 (2012-09-26)
The oriental fruit fly, Bactrocera dorsalis, is a major pest that infects fruits and agricultural products worldwide. The latest resistance monitoring of B. dorsalis from mainland China has identified high levels of resistance to insecticides. In this study, the biochemical
Anping Zhang et al.
Journal of chromatography. A, 1281, 26-31 (2013-02-13)
Chiral separation mechanism determination and absolute configuration assignment are fundamental to the development of chiral stationary phases (CSPs) and the evaluation of both the enantioselective bioactivity and fate of chiral compounds. This work investigated the process of chiral separation and
Leslie C Alvarez et al.
Journal of medical entomology, 50(5), 1031-1039 (2013-11-05)
Resistance to the insecticides deltamethrin and malathion and the enzymes associated with metabolic resistance mechanisms were determined in four field populations of Aedes aegypti (L.) from western Venezuela during 2008 and 2010 using the bottle assay and the microplate biochemical
William R Brogan et al.
Environmental toxicology and chemistry, 32(7), 1535-1543 (2013-04-09)
Some submersed macrophyte species rapidly sorb some insecticides from the water, potentially reducing exposure for aquatic species. The rates at which macrophytes remove insecticides, however, can differ widely among plant species. Furthermore, few studies have examined how much macrophytes actually
Christopher J Salice et al.
Ecotoxicology (London, England), 22(1), 42-49 (2012-10-12)
Ecological receptors are faced with a multitude of stressors that include abiotic and biotic factors creating a challenge for assessing risk of chemical exposure. Of particular interest and importance are the effects of contaminants on inter-species interactions such as competition
Shereene Idriss et al.
Journal of drugs in dermatology : JDD, 8(8), 715-720 (2009-08-12)
Malathion is an under-recognized and under-utilized therapy for head lice and scabies largely due to misperceptions about its safety profile. Specifically, its pure form as it exists in pharmaceutical preparations is non-toxic to humans in the low doses available. While
P Flessel et al.
Environmental and molecular mutagenesis, 22(1), 7-17 (1993-01-01)
Mammalian in vivo and in vitro studies of technical or commercial grade malathion and its metabolite malaoxon show a pattern of induction of chromosome damage, as measured by chromosome aberrations, sister chromatid exchanges, and micronuclei. Experiments with purified (> 99%)
Zhichao Liu et al.
PLoS computational biology, 7(12), e1002310-e1002310 (2011-12-24)
Drug-induced liver injury (DILI) is a significant concern in drug development due to the poor concordance between preclinical and clinical findings of liver toxicity. We hypothesized that the DILI types (hepatotoxic side effects) seen in the clinic can be translated
David Jira et al.
Neuro endocrinology letters, 33 Suppl 3, 53-59 (2013-01-29)
Malathion is generally not classified as toxic. However, the toxicity seems to be species-dependent. Local and systemic toxicity data for birds are rare, but a decrease of wild bird densities in areas where malathion was applied was reported. Aim of
Banugopan Kesavaraju et al.
Journal of medical entomology, 49(5), 988-992 (2012-10-03)
Malathion is an organophosphate insecticide that is used for the control of adult mosquitoes and agricultural pests. Recent studies have shown that malathion affects competition among mosquitoes in the larval stage. Individuals from laboratory colonies are often used in experiments
Anupama Ojha et al.
Environmental toxicology, 28(10), 543-552 (2011-07-26)
Organophosphate pesticides are among the most widely used synthetic chemicals for controlling a wide variety of pests. Chlorpyrifos (CPF), methyl parathion (MPT), and malathion (MLT) are among the most extensively used organophosphate (OP) pesticides. The main target of action of
Hamid Karyab et al.
Bulletin of environmental contamination and toxicology, 90(1), 126-131 (2012-11-08)
A questionnaire study and field visit showed that diazinon and malathion were the most commonly used pesticides in Qazvin province, Iran. Concentrations of these pesticides were determined in water sources; include springs, wells and Shahrood River. Springs water samples had
Dechen Pemo et al.
The Southeast Asian journal of tropical medicine and public health, 43(6), 1339-1345 (2013-02-19)
We conducted this study to determine the insecticide susceptibility of two malaria vectors, Anopheles dirus and Anopheles minimus from Kanchanaburi Province, Thailand. The mosquitoes were collected and reared under laboratory conditions. The test was carried out on unfed F-1 female
D L Sudakin et al.
Journal of toxicology. Clinical toxicology, 38(1), 47-50 (2000-03-04)
A 33-year-old female ingested an unknown quantity of malathion in a suicide attempt. Cholinergic signs consistent with severe organ, phosphate intoxication developed and were treated within 6 hours of ingestion. Intravenous atropine and a continuous infusion of pralidoxime (400 mg/h)
Qingli Shang et al.
Environmental toxicology, 29(5), 526-533 (2012-04-11)
Aphis gossypii (Glover) has been found to possess multiple mutations in the acetylcholinesterase (AChE) gene (Ace) that might involve target site insensitivity. In vitro functional expression of AChEs reveals that the resistant Ace1 (Ace1R) and Ace2 (Ace2R) were significantly less
Droplet size characterization of three aerial malathion spray programs.
T Younglove et al.
Bulletin of environmental contamination and toxicology, 53(4), 493-500 (1994-10-01)
Serpil Mişe Yonar et al.
Ecotoxicology and environmental safety, 102, 202-209 (2014-02-01)
The present study investigated the potential ameliorative effects of propolis against malathion toxicity in the blood and various tissues of carp. The fish were exposed to sublethal concentrations of malathion (0.5 and 1 mg/L) for 10 days, and propolis (10
Nashwa H Kamel et al.
Journal of the Egyptian Society of Parasitology, 43(1), 245-258 (2013-05-24)
This work monitored changes in some digestive enzymes (trypsin and aminopeptidase) associated with the building up of resistance in Cx. pipiens larvae to two chemical insecticides (methomyl and/or malathion) and one biological insecticide (Bacillus thuringiensis-H14 or B.t H 14). The
Lorin A Neuman-Lee et al.
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes, 48(6), 442-448 (2013-03-05)
This study examined the effects of sub-lethal exposure of the ubiquitous pesticide malathion on the behavior of the model orthopteran species, the house cricket (Acheta domesticus). Increasing concentrations of malathion caused male crickets to increase periods of non-directional movement, such
Shuangying Yu et al.
Environmental toxicology and chemistry, 32(9), 2056-2064 (2013-05-21)
It has been suggested that Xenopus laevis is less sensitive than other amphibians to some chemicals, and therefore, that the Frog Embryo Teratogenesis Assay-Xenopus (FETAX) may have limited use in risk assessments for other amphibians. However, comparisons are based mostly
M A Iudin et al.
Eksperimental'naia i klinicheskaia farmakologiia, 76(1), 21-24 (2013-03-07)
The kinetics of oxime-induced reactivation of malathion-inhibited cholinesterase has been experimentally studied in vitro. It is shown that oximes do not restore the activity of inhibited butyrylcholinesterase. Acetylcholinesterase reactivation peak (5-mins long) was found to take place upon introduction of
V V Vorob'eva et al.
Eksperimental'naia i klinicheskaia farmakologiia, 75(8), 25-30 (2012-09-28)
The mechanisms of protective action of thiobenzimidazole derivatives metaprot and ethomerzol (25 and 50 mg/kg) have been studied on a model of carbophos intoxication (256.0 +/- 8.7 mg/kg) in rats. Both compounds recovered the resistance to physical loads in forced
Najwa Ben Oujji et al.
Sensors (Basel, Switzerland), 12(6), 7893-7904 (2012-09-13)
This work presents the development of bioassays and biosensors for the detection of insecticides widely used in the treatment of olive trees. The systems are based on the covalent immobilisation of acetylcholinesterase on magnetic microbeads using either colorimetry or amperometry
Baljinder Singh et al.
Critical reviews in microbiology, 40(2), 146-154 (2013-02-28)
Organophosphorus pesticide, malathion, is used in public health, residential, and agricultural settings worldwide to control the pest population. It is proven that exposure to malathion produce toxic effects in humans and other mammals. Due to high toxicity, studies are going
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