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Niraj Pant et al.
Environmental science and pollution research international, 21(18), 11066-11074 (2014-05-13)
Environmental toxicants viz lead or cadmium and phthalate esters (di(2-ethylhexyl) phthalate [DEHP], dibutyl phthalate [DBP], and diethyl phthalate [DEP]) widely found in different environmental strata are linked to deteriorating male reproductive health. The objective was to assess the relationships between
Hong Ma et al.
Zhonghua nan ke xue = National journal of andrology, 18(9), 783-788 (2012-12-01)
To investigate the influences of di-2-ethylhexyl phthalate (DEHP) and its metabolite single-ethylhexyl phthalate (MEHP) on the expression of transforming growth factor-beta 1 (TGF-beta1) and telomerase activity in young male Wistar Ninety-six 2-week-old male Wistar rats were equally randomized into a
Wei Jia et al.
Journal of chromatography. A, 1362, 110-118 (2014-08-27)
A new analytical method was developed and validated for simultaneous analysis of 27 phthalates in milk and milk products. Response surface methodology was employed to optimize a quick, easy, cheap, effective, rugged, and safe (QuEChERS) sample preparation method. Ultrahigh-performance liquid
Jingjing Guo et al.
Toxicology, 306, 9-15 (2013-02-09)
The objective of the present study is to determine whether di(2-ethylhexyl) phthalate (DEHP) exposure at adulthood increases rat Leydig cell number and to investigate the possible mechanism. 90-day-old Long-Evans rats were randomly divided into 3 groups, and were gavaged with
J W Chang et al.
Environmental pollution (Barking, Essex : 1987), 189, 77-84 (2014-03-19)
Phthalates strongly and adversely affect reproduction, development and liver function. We did a cumulative risk assessment for simultaneous exposure to nine phthalates using the hazard index (HI) and the levels of nine phthalates in 1200 foodstuff samples. DEHP (di-2-ethylhexyl phthalate)
Yu Lu et al.
Toxicological sciences : an official journal of the Society of Toxicology, 139(2), 317-327 (2014-03-29)
The aim of the present research was to explore whether food emulsifier polysorbate 80 can enhance the absorption of di-(2-ethylhexyl) phthalate (DEHP) and its possible mechanism. We established the high-performance liquid chromatography (HPLC) method for detecting DEHP and its major
Miriany Avelino Moreira et al.
Food chemistry, 178, 195-200 (2015-02-24)
Plasticisers are compounds used in the polymer industry to increase the flexibility of plastics. Some of these compounds cause endocrine dysfunction in humans and animals by interfering with the production, release, transport, metabolism, binding or elimination of natural hormones in
Outi Huttala et al.
ALTEX, 36(3), 419-434 (2019-03-18)
Besides being an energy storage, adipose tissue is an endocrine organ closely associated with vascular system. Human relevant in vitro models are needed to study adipose tissue and related diseases. Vasculature plays a central role in the development and inhibition
Urine chemical content may be a false measure of environmental exposure.
Robert L Brent
Pediatrics, 132(3), e747-e748 (2013-08-21)
Hiroshi Toda et al.
Applied and environmental microbiology, 81(6), 1919-1925 (2015-01-04)
We describe the development of biocatalysis for producing optically pure straight-chain (S)-epoxyalkanes using styrene monooxygenase of Rhodococcus sp. strain ST-10 (RhSMO). RhSMO was expressed in the organic solvent-tolerant microorganism Kocuria rhizophila DC2201, and the bioconversion reaction was performed in an
Teresa Cirillo et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 51, 434-438 (2012-10-31)
Ready-to-eat packed meals intended to hospital patients were studied over a two-weeks period to measure the contents of di-(2-ethylhexyl) phthalate (DEHP) and di-n-butylphthalate (DBP) and to evaluate their daily intake by total diet. The packaging consisted of polyethylene terephthalate (PET)
Tsanta Radaniel et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 965, 158-163 (2014-07-16)
Searching for alternatives to di-(2-ethylhexyl)-phthalate, a plasticizer that has been widely used in the manufacturing of PVC medical devices, has become a major challenge since a European regulation underlined some clinical risks. The aim of this study is to develop
S Magdouli et al.
Journal of environmental management, 127, 36-49 (2013-05-18)
Phthalates are being increasingly used as softeners-plasticizers to improve the plasticity and the flexibility of materials. Amongst the different plasticizers used, more attention is paid to di (2-ethylhexylphtalate) (DEHP), one of the most representative compounds as it exhibits predominant effects
W J Choi et al.
The British journal of dermatology, 171(4), 854-860 (2014-03-13)
Concerns have emerged about the adverse effect of phthalates on human health. The aim of this study was to investigate the association between di(2-ethylhexyl) phthalate (DEHP) exposure and atopic dermatitis (AD) in Korean children, focusing on the potential dose-response relationship.
Jing-Cai Liu et al.
Journal of pineal research, 67(1), e12577-e12577 (2019-04-03)
This study, using an in vitro ovary culture model, investigates the mechanisms through which di(2-ethylhexyl)phthalate (DEHP) impairs germ cell cyst breakdown and primordial follicle assembly. The results indicate the latter effects exerted by 10 or 100 µmol/L DEHP in cultured newborn
Mais Al-Natsheh et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 985, 103-109 (2015-02-11)
A gas chromatography/mass spectrometric method was developed for the simultaneous determination of eight phthalic acid esters (PAEs) in toys and child care articles that are made of plasticized plastic. The novel method was used to determine the total concentration of
Anima Tripathi et al.
Zygote (Cambridge, England), 27(4), 203-213 (2019-07-13)
The present study investigated if the presence of encircling granulosa cells protected against di(2-ethylhexyl)phthalate (DEHP)-induced oxidative stress in rat oocytes cultured in vitro. Denuded oocytes and cumulus-oocyte complexes (COCs) were treated with or without various doses of DEHP (0.0, 25.0
E Campioli et al.
Nutrition & diabetes, 4, e115-e115 (2014-05-07)
Di-(2-ethylhexyl) phthalate (DEHP) is a plasticizer used to increase the flexibility of polyvinyl chloride. DEHP and its active metabolite mono-(2-ethylhexyl) phthalate are detected in many biological fluids during fetal and postnatal life. In rodent models, in utero DEHP exposure has
Teresa Cirillo et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 30(2), 403-411 (2012-11-29)
Ready-to-eat meals packed in polyethylene terephthalate (PET) and aluminium dishes, supplied to patients in two hospitals in the Campania region (Italy), were studied to evaluate the probable migration of di-n-butylphthalate (DBP) and di(2-ethylhexyl)phthalate (DEHP) from the packaging into the food.
Y Xu et al.
Indoor air, 25(1), 79-92 (2014-04-29)
Retail stores contain a wide range of products that can emit a variety of indoor pollutants. Among these chemicals, phthalate esters and polybrominated diphenyl ethers (PBDEs) are two important categories of semi-volatile organic compounds (SVOCs). Filters in heating, ventilation, and
Patrick R Hannon et al.
Toxicology and applied pharmacology, 284(1), 42-53 (2015-02-24)
Di(2-ethylhexyl) phthalate (DEHP) is a ubiquitous environmental toxicant found in consumer products that causes ovarian toxicity. Antral follicles are the functional ovarian units and must undergo growth, survival from atresia, and proper regulation of steroidogenesis to ovulate and produce hormones.
W J Morton et al.
Anaesthesia, 68(4), 377-381 (2013-01-03)
Phthalates are chemicals used extensively in the manufacture of plastics for their desirable physical characteristics. In addition to enhancing the performance of plastics, phthalates have a number of undesirable effects, principally endocrine disruptor effects, that may have adverse effects on
Taewoo Yum et al.
Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering, 48(8), 912-917 (2013-03-15)
Endocrine disruptors that mimic natural hormones and inhibit the action of hormones have recently attracted attention as one of the main cause of precocious puberty. In this study, the levels of 7 EDCs and 3 isoflavones that exhibit estrogen-like actions
Mir Ali Farajzadeh et al.
Journal of chromatography. A, 1379, 24-33 (2015-01-04)
In this study, for the first time, a dispersive liquid-liquid microextraction technique using a ternary solvent mixture is reported. In order to extract five phthalate esters and di(2-ethylhexyl) adipate with different polarities from aqueous samples, a simplex centroid experimental design
Jihyun Lee et al.
Environment international, 73, 312-322 (2014-09-13)
The present study aims to investigate how resource strategies, which intend to reduce waste and increase recycling, influence on human exposure to hazardous chemicals from material recycling. In order to examine the flows of hazardous chemicals in recycled material, a
Jun-Jie Wang et al.
Theranostics, 11(10), 4992-5009 (2021-03-24)
Rationale: Accumulated evidence indicates that environmental plasticizers are a threat to human and animal fertility. Di (2-ethylhexyl) phthalate (DEHP), a plasticizer to which humans are exposed daily, can trigger reproductive toxicity by acting as an endocrine-disrupting chemical. In mammals, the
Jing-Cai Liu et al.
Environmental pollution (Barking, Essex : 1987), 270, 116088-116088 (2020-11-26)
It is known that Di (2-ethylhexyl) phthalate (DEHP) may impact mammalian reproduction and that in females one target of the drug's action is follicle assembly. Here we revisited the phthalate's action on the ovary and from bioinformatics analyses of the
Yu Han et al.
Toxicology, 324, 88-97 (2014-08-06)
Di-(2-ethylhexyl) phthalate (DEHP) has been considered as a widespread environmental persistent organic pollutant and its potential concern on human health is raised by previous studies. In particular, children are more likely to be exposed to DEHP through gastrointestinal route and
Yuji Haishima et al.
Journal of biomedical materials research. Part A, 101(9), 2630-2643 (2013-02-16)
This study examines the chemical, physicochemical, and biological properties of PVC sheets treated with UV irradiation on their surfaces to suppress the elution of a plasticizer, di-(2-ethylhexyl) phthalate (DEHP), for developing novel polyvinyl chloride (PVC) medical devices. The PVC sheets
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