Merck
Search Within
Applications
Content Type

Calibration, qualification, and validation

Applied Filters:
facet applications:Calibration, qualification, and validation
facet content type:Technical Article
Extraction of Permethrin Pesticides from Spinach Using QuEChERS Methodology with Automated Shaking
Extraction of Permethrin Pesticides from Spinach Using QuEChERS Methodology with Automated Shaking
Certified Reference Materials for ¹⁹F Quantitative NMR Ensuring Traceability to “The International System of Units” (SI)
In certain cases, 1H qNMR reaches its limits, especially regarding the certification of complex and larger molecules. However, new fields of application often also bring along the presence of heteroatoms, namely 31P and 19F. We therefore introduced 3 CRMs for
Hopane Reference Standards for use as Petrochemical Biomarkers in Oil Field Remediation and Spill Analysis
We provide high-quality, relevant hopane reference standards to be used as biomarkers for petrochemical oil field remediation and spill analysis.
High-Performance Quantitative H-1 NMR
The signal ratio of two different protons can be measured with tremendous precision, which enables the generation of certified reference materials for use as qNMR standards.
Petroleum Hydrocarbon Standards for SIMDIS Analyses
Understanding the boiling point range distribution of petrochemical products is critical for selection of the proper method to process feed stocks, for process control, for contaminant identification and for development of new test methods.
New cis/trans FAME Standard for Optimising GC System Performance
AOCS and AOAC methods for determining the trans fatty acid composition of foods by gas chromatography require the use of a highly polar cyanosilicone capillary column to provide the best peak resolution attainable of the numerous geometric (cis & trans)
Columns and Analytical Standards for Protein SEC
Size-exclusion chromatography (SEC) columns and ready-to-use standards facilitate method development and increase robustness of protein SEC methods.
ICP-MS Analysis of Heavy Metals in Hemp Containing Personal Care Products
Analysis of heavy metals and metals in cannabis and hemp containing personal care products and cosmetics include sample preparation by grinding, preparation of calibration solutions for a standard addition approach, a microwave digestion protocol and subsequent ICP-MS analysis.
Cannabinoid Analysis of Hemp: Developing an Efficient HPLC Method Workflow
Several different HPLC method options are explored for the efficient and time effective analysis of cannabinoids in a sample of hemp flower. The differences between gradient and isocratic analyses are explored, and the two methods are compared in determining the
New Certified Reference Materials for α‑Lactalbumin, β‑Lactoglobulin A & B, and Lactoferrin
We have developed Certified Reference Materials (CRMs) of fully intact milk proteins that allow accurate testing of the most critical proteins in infant formula; help labs to develop and test infant formula products with high accuracy, while ensuring legal and
Cannabinoid Certified Reference Materials (CRMs) for an Improved Testing Accuracy and Traceability
We offer a portfolio of cannabinoid CRMs such as THC and THCA, available as single component solutions or mixes, certified in accordance with ISO 17034 and ISO/IEC 17025 for accurate cannabinoid profiling and potency testing.
Extractables Study with LC-UV/MS
Reliable identification and quantification of unknown extractables of a single-use system (SUS) with a 21 component CRM mix for liquid chromatography (LC-UV/MS) methods using Ascentis® C18 column.
Chiral and Achiral LC-MS Analysis of Warfarin™ in Plasma Samples
Clinical laboratories are beginning to reap the benefits of LC-MS in terms of its sensitivity, specificity, throughput, and potential to reduce cost per sample. The purpose of this study was to demonstrate the LC-MS analysis of Warfarin in plasma samples
Analysis of Tetrahydrocannabinol (THC) and Carboxytetrahydrocannabinol (THCCOOH) in Surface Waters by SPME and GC/MS
Analysis of Tetrahydrocannabinol (THC) and Carboxytetrahydrocannabinol (THCCOOH) in Surface Waters by SPME and GC/MS
Radiello Diffusive Sampler for Monitoring 1,3-Butadiene and Isoprene in Workplace Air
The manufacturing of elastomers makes wide use of 1,3-butadiene (CAS No. 106-99-0) and isoprene (2-methyl- 1,3-butadiene, CAS No. 78-79-5). Both compounds are classifi ed as carcinogenic by the International Agency for Research on Cancer (IARC). 1,3-Butadiene is currently listed in
Melamine Analysis via GC-MS
Sigma-Aldrich presents an article about the analysis of melamine and related compounds in dog food with the use of more economical gas chromatography-mass spectrometry (GC-MS) instrumentation.
Improving the Current USP Method for the Analysis of Lansoprazole Drug Substance Using HPLC Columns Based on Fused-Core® Particle Technology
Compendial methods from the USP (United States Pharmacopeia) are widely used in pharmaceutical drug product and raw materials testing. However, not all methods in the USP use modern technologies. In chromatographic methods, it is not uncommon that older brands of
An LC/MS Peptide Standard for Rapid System Suitability Assessment and Retention Time Translation Across LC/MS Platforms
Standards are critical in liquid chromatography/mass spectrometry (LC/MS) based proteomics to ensure optimal and consistent system performance before, during, and after sample analysis.
Isotopic Labeling for NMR Spectroscopy of Biological Solids
Isotopic Labeling for NMR Spectroscopy of Biological Solids;
GC Analysis of a 37-Component FAME Mix on Omegawax®
This technical article will discuss GC Analysis of a 37-Component FAME Mix on Omegawax.
HPLC Separation of Ginsenosides from American Ginseng
The HPLC method for ginsenoside separation was optimized using a ginsenoside standard mixture and then applied to a sample of American Ginseng root. The experimental conditions and chromatograms are shown.
Titripac® Sustainable Packaging for Ready-to-Use Certipur® pH Buffers
Learn about our ready-to-Use Certipur® pH Buffer solutions (4 L & 10 L), available in an innovative Titripac® sustainable packaging for a wide pH range of 1 to 12.
Solution with 17 Amino Acids as TraceCERT® Certified Reference Material
Technical article on "Solution with 17 Amino Acids as TraceCERT® Certified Reference Material"
Comparison of QuEChERS Products for the Extraction of Planar Pesticides from Spinach
Supel™ QuE Verde combines a novel carbon with zirconia coated silica (Z-Sep+) to provide an optimum balance between planar pesticide recovery and color removal.
Importance of Volumetric Solution Standardization
The titer determination or standardization of a titration solution is essential for accurate and reliable titration results.
Vitamin D epi-Metabolites Separated with HybridSPE-Phospholipid
This Sigma-Aldrich article continues to detail new methodology for the analysis of Vitamin D metabolites using HybridSPE-Phospholipid technology.
Drinking Water Testing by Ion Chromatography using Ultrapure Water
This study reviews the suitability of ultrapure water for the IC analysis of drinking water. Inorganic ions and disinfectant by-products (DBPs) were assessed.
Analysis of California Cannabis List of Pesticides, Mycotoxins, and Pyrethrins Using Ascentis® Express Biphenyl Column
Cannabis testing regulations include analysis of purity, potency, and contaminants. Learn more about analysis of cannabis for pesticides, mycotoxins, and pyrethrins registered in California by LC-MS/MS and GC-MS/MS Using Ascentis® Express Biphenyl and SLB®-5ms Columns
Complete Workflow for the Analysis of California List of Pesticides in Cannabis by LC-MS/MS and GC-MS/MS
To show product safety, it is mandatory to test cannabis flowers for the presence of pesticides. In this article, we show a complete workflow for sample preparation and analysis of cannabis for the pesticides registered in California, by LC-MS/MS and
NMR Deuterated Solvent Properties Reference Chart
Use this reference table to find the coupling values and chemical shifts of our NMR (deuterated) solvents. Melting and boiling points, molecular weight, density, and CAS number are also listed.
Page 1 of 3