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Content Type:Technical Article
Showing 1-11 of 11 results
EX-CELL® Advanced™ CHO Fed-Batch System – Bioprocessing Technology Institute, Singapore Case Study
In this study, nine commercially available, chemically defined media and feed combinations from different vendors were assessed for producing monoclonal antibody in Chinese hamster ovary (CHO) cells.
Choosing the optimal cell culture media for vaccine production
Cultured cells are excellent hosts for the propagation of many types of viruses. The ability of cell culture systems to produce large quantities of attenuated viral particles has served as the basis for the production of both human and veterinary
Speeding Biosimilar Development using Glycosylation Control Technology from SAFC
The biosimilar market is expected to grow rapidly in the coming years, as many blockbuster monoclonal antibodies lose patent protection by 2020.
Quantification of Host Cell Proteins
Residual presence of host cell proteins (HCPs) in recombinant therapeutic products has considerable clinical safety risks associated with a potential immunological response in patients.
Selection Process Development in a GS Knock-Out CHO Host Cell Line: The Effects of MSX Addition on Clones Generated in an MSX-Free Process
The Glutamine Synthetase (GS) expression system does not typically require multiple rounds of amplification to isolate high-producing clones (Brown, 1992).
Protein Expression Systems
The development of genetic engineering and cloning has opened many possibilities of expression and isolation of heterologous proteins for research purposes. Considerable advances in technology have enabled expression and isolation of recombinant proteins in large scale.
EX-CELL® Glycosylation Adjust (GAL+)
Our protein quality supplement, EX-CELL® Glycosylation Adjust (Gal+), provides customers with a novel chemically defined product which targets glycosylation attributes.
Modified Amino Acids
Modified amino acids are inhouse manufactured amino acid derivatives with specific properties enabling the intensification of cell culture processes.
CHO Platform
We have developed a number of tools that allow you to develop optimized media formulations for your specific CHO clones faster and easier than ever before.
Using Microarray Technology to Select Housekeeping Genes in Chinese Hamster Ovary Cells
In the present study, we have identifi ed species-specifi c housekeeping genes (HKGs) for Chinese Hamster Ovary (CHO) cells using data from microarray gene expression profiling.
Choosing the Optimal Cell Culture Media for Vaccine Production
Choosing the Optimal Cell Culture Media for Vaccine Production