APP
amyloid beta (A4) precursor protein
Sinônimos:
AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2
Espécies:
Human APP (351), Mouse App (11820), Rat App (54226), fruit fly app (39399), chicken APP (374198), dog APP (403407), domestic cat APP (101085564), cow APP (280722), sheep APP (101111593), domestic guinea pig App (100715302)
ID UniProtKB:
ID do gene:
- Human(351) Summary: This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(11820) amyloid beta (A4) precursor protein
- Rat(54226) amyloid beta (A4) precursor protein
- fruit fly(39399) approximated
- chicken(374198) amyloid beta (A4) precursor protein
- dog(403407) amyloid beta (A4) precursor protein
- domestic cat(101085564) amyloid beta (A4) precursor protein
- cow(280722) amyloid beta (A4) precursor protein
- sheep(101111593) amyloid beta (A4) precursor protein
- domestic guinea pig(100715302) amyloid beta (A4) precursor protein
- naked mole-rat(101724743) amyloid beta (A4) precursor protein
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Número do produto
Descrição
Espécies
Human APP / Amyloid Beta A4 Protein ELISA Kit, for serum, plasma, cell culture supernatants and urine,
Espécies
human
Small Molecule - Antagonist
Antibodies
Número do produto
Descrição
Reatividade de espécies
Aplicação
Anticorpo antiAPP A4, a.a. 66-81 de APP {NT}, clone 22C11, clone 22C11, Chemicon®, from mouse,
Reatividade de espécies
canine, fish, human, monkey, mouse, pig, rat
Aplicação
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anticorpo antiβ-amiloide, clone W0-2, clone WO2, from mouse,
Reatividade de espécies
human, mouse
Aplicação
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-β-Amyloid antibody, Mouse monoclonal, clone BAM-10, ascites fluid,
Reatividade de espécies
human
Aplicação
ELISA
immunohistochemistry
immunohistochemistry
Anticorpo anti-beta-amiloide 1-42, Chemicon®, from rabbit,
Reatividade de espécies
chicken, human, mouse
Aplicação
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anticorpo antioligômero amiloide, αβ,oligomérico, serum, Chemicon®,
Reatividade de espécies
eukaryotes, human, mouse, rat
Aplicação
ELISA
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
Proteins
Número do produto
Descrição
Espécies