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Merck

BAD

BCL2-associated agonist of cell death

Sinônimos:
BBC2, BCL2L8
Espécies:
ID UniProtKB:
ID do gene:
  • Human(572) Summary: The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq, Jul 2008]
  • Mouse(12015) BCL2-associated agonist of cell death
  • Rat(64639) BCL2-associated agonist of cell death
  • dog(483763) BCL2-associated agonist of cell death
  • domestic cat(768269) BCL2-associated agonist of cell death
  • sheep(780444) BCL2-associated agonist of cell death
  • cow(615013) BCL2-associated agonist of cell death
  • naked mole-rat(101726042) BCL2-associated agonist of cell death
  • domestic guinea pig(100734151) BCL2-associated agonist of cell death

Custom & Knockdown Gene Products

Small Molecule - Antagonist

Número do produto
Descrição
Espécies
2,3-Dihydroxynaphthalene, ≥98.0% (HPLC),
Espécies
human
4-Biphenylacetic acid, 98%,
Espécies
human
Biphenyl-4-carboxylic acid, 95%,
Espécies
human
(±)-Gossypol from cotton seeds, ≥95% (HPLC),
Espécies
human

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-BAD antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
immunohistochemistry

western blot
Anti-phospho BAD Antibody (Ser155), from rabbit, purified by affinity chromatography,
Reatividade de espécies
bovine, canine, human, mouse, rat
Aplicação
immunoprecipitation (IP)
inhibition assay

western blot
Anti-Phospho-Bad-S112 antibody produced in rabbit, ,
Reatividade de espécies
human
Aplicação
western blot
Anti-Phospho-Bad-S155 antibody produced in rabbit, ,
Reatividade de espécies
human
Aplicação
western blot
Anti-Phospho- Bad (Ser75) Antibody, from rabbit,
Reatividade de espécies
human, mouse, rat
Aplicação
western blot

Proteins

Número do produto
Descrição
Espécies
BAD, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human BAD,
Espécies
human