CDC27
cell division cycle 27
Sinônimos:
ANAPC3, APC3, CDC27Hs, D0S1430E, D17S978E, HNUC, NUC2
Espécies:
Human CDC27 (996), Mouse Cdc27 (217232), Rat Cdc27 (360643), naked mole-rat Cdc27 (101717421), domestic cat CDC27 (101091234), fruit fly Cdc27 (38798), dog CDC27 (490924), chicken CDC27 (419960), cow CDC27 (540660), domestic guinea pig Cdc27 (100731091) ...Mais
ID UniProtKB:
ID do gene:
- Human(996) Summary: The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. This protein was shown to interact with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1, and thus may be involved in controlling the timing of mitosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(217232) cell division cycle 27
- Rat(360643) cell division cycle 27
- naked mole-rat(101717421) cell division cycle 27
- domestic cat(101091234) cell division cycle 27 homolog (S. cerevisiae)
- fruit fly(38798) CG8610 gene product from transcript CG8610-RB
- dog(490924) cell division cycle 27 homolog (S. cerevisiae)
- chicken(419960) cell division cycle 27 homolog (S. cerevisiae)
- cow(540660) cell division cycle 27 homolog (S. cerevisiae)
- domestic guinea pig(100731091) cell division cycle 27
- Zebrafish(30450) cell division cycle 27
- Horse(100054552) cell division cycle 27 homolog (S. cerevisiae)
- sheep(101121276) cell division cycle 27 homolog (S. cerevisiae)
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Antibodies
Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-CDC27 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reatividade de espécies
human
Aplicação
immunofluorescence
Anti-CDC27 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-CDC27 Antibody, clone 7U5A3, Rabbit Monoclonal, ,
Reatividade de espécies
human, rat
Aplicação
western blot
Anti-Cdc27 antibody,Mouse monoclonal, clone AF3.1, purified from hybridoma cell culture,
Reatividade de espécies
xenopus, bovine, canine, human, mouse, rat
Aplicação
ELISA
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
microarray
western blot
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
microarray
western blot