Pular para o conteúdo
Merck

CDK9

cyclin-dependent kinase 9

Sinônimos:
C-2k, CDC2L4, CTK1, PITALRE, TAK
Espécies:
ID UniProtKB:
ID do gene:
  • Human(1025) Summary: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. [provided by RefSeq, Jul 2008]
  • Mouse(107951) cyclin-dependent kinase 9 (CDC2-related kinase)
  • Rat(362110) cyclin-dependent kinase 9
  • domestic guinea pig(100725846) cyclin-dependent kinase 9
  • naked mole-rat(101722666) cyclin-dependent kinase 9
  • sheep(101109788) cyclin-dependent kinase 9
  • Zebrafish(321602) cyclin-dependent kinase 9 (CDC2-related kinase)
  • cow(520580) cyclin-dependent kinase 9
  • dog(491325) cyclin-dependent kinase 9
  • chicken(417226) cyclin-dependent kinase 9
  • fruit fly(37586) Cyclin-dependent kinase 9
  • domestic cat(101097767) cyclin-dependent kinase 9

Custom & Knockdown Gene Products

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-CDK9, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human
Aplicação
immunohistochemistry
western blot
Anti-phospho-CDK9 (pThr186) antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
western blot
Anti-CDK9 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
ChIP
immunofluorescence

immunohistochemistry
Anti-CDK9 antibody produced in rabbit, ,
Reatividade de espécies
Aplicação
immunohistochemistry
western blot
Anti-CDK9 Antibody, clone 1F9 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reatividade de espécies
human, monkey, mouse, rat
Aplicação
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot

Small Molecule - Inhibitor

Número do produto
Descrição
Espécies
Flavopiridol hydrochloride hydrate, ≥98% (HPLC), powder,
Espécies
human
Roscovitine, ≥98% (TLC),
Espécies
human, mouse, rat
Olomoucine, ≥98% (HPLC),
Espécies
human, rat

Proteins

Número do produto
Descrição
Espécies
Cdk9/Cyclin T1 Protein, active, 10 µg, Active, C-terminal 6His-tagged, full length recombinant, human Cdk9 co-expressed with untagged, full-length human Cyclin T1, for use in Kinase Assays.,
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human CDK9,
Espécies
human