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Merck

CSTB

cystatin B (stefin B)

Sinônimos:
CST6, EPM1, EPM1A, PME, STFB, ULD
Espécies:
ID UniProtKB:
ID do gene:
  • Human(1476) Summary: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1). [provided by RefSeq, Jul 2008]
  • Mouse(13014) cystatin B
  • Rat(25308) cystatin B (stefin B)
  • domestic guinea pig(100719016) cystatin B (stefin B)
  • naked mole-rat(101699171) cystatin B (stefin B)
  • cow(514170) cystatin B (stefin B)
  • cow(512805) cystatin B (stefin B)
  • dog(478424) cystatin B (stefin B)
  • chicken(418267) cystatin B (stefin B)
  • sheep(101123265) cystatin B (stefin B)

Custom & Knockdown Gene Products

ELISA

Número do produto
Descrição
Espécies
Human Cystatin B ELISA, for serum, plasma and cell culture supernatants,
Espécies
human

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-CSTB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
immunohistochemistry

western blot
Anti-CSTB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
Monoclonal Anti-CSTB antibody produced in mouse, clone M1-C1, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
ELISA
western blot

Proteins

Número do produto
Descrição
Espécies
Cystatin B human, recombinant, expressed in E. coli,
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human CSTB,
Espécies
human
MISSION® esiRNA, targeting mouse Cstb,
Espécies
mouse