Pular para o conteúdo
Merck

CYBB

cytochrome b-245, beta polypeptide

Sinônimos:
AMCBX2, CGD, GP91-1, GP91-PHOX, GP91PHOX, NOX2, p91-PHOX
Espécies:
Human CYBB (1536), Mouse Cybb (13058), Rat Cybb (66021), cow CYBB (281112), sheep CYBB (100036757), Domestic Rabbit CYBB (100008801), dog CYBB (491825), chicken CYBB (418581), Zebrafish cybb (393386)
ID UniProtKB:
P04839, A8K138, Q2PP16
ID do gene:
  • Human(1536) Summary: Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole. [provided by RefSeq, Jul 2008]
  • Mouse(13058) cytochrome b-245, beta polypeptide
  • Rat(66021) cytochrome b-245, beta polypeptide
  • cow(281112) cytochrome b-245, beta polypeptide
  • sheep(100036757) cytochrome b-245, beta polypeptide
  • Domestic Rabbit(100008801) cytochrome b-245 beta polypeptide
  • dog(491825) cytochrome b-245, beta polypeptide (chronic granulomatous disease)
  • chicken(418581) cytochrome b-245, beta polypeptide
  • Zebrafish(393386) cytochrome b-245, beta polypeptide (chronic granulomatous disease)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
MABS2195
Anti-gp91phox (NOX2) Antibody, ,
Reatividade de espécies
human
Aplicação
flow cytometry
western blot
SAB5702937
Anti-NOX2/gp91phox Antibody, clone 2Y8W3, Rabbit Monoclonal, ,
Reatividade de espécies
human, mouse, rat
Aplicação
western blot
07-024
Anti-gp91-phox Antibody, Upstate®, from rabbit,
Reatividade de espécies
human
Aplicação
western blot
MABS2193
Anti-gp91phox (NOX2) Antibody, ,
Reatividade de espécies
human
Aplicação
flow cytometry
inhibition assay
western blot
SAB4300724
Anti-CYBB antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
western blot

esiRNA

Número do produto
Descrição
Espécies
EHU010941
MISSION® esiRNA, targeting human CYBB,
Espécies
human