DNMT3L
DNA (cytosine-5-)-methyltransferase 3-like
Sinônimos:
Espécies:
Human DNMT3L (29947), Mouse Dnmt3l (54427), Rat Dnmt3l (309680), dog DNMT3L (608536), domestic cat DNMT3L (101091300), cow DNMT3L (613785), sheep DNMT3L (101102451), naked mole-rat Dnmt3l (101719207), domestic guinea pig Dnmt3l (100729608), Horse DNMT3L (100050680)
ID UniProtKB:
ID do gene:
- Human(29947) Summary: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases, but is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, it does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012]
- Mouse(54427) DNA (cytosine-5-)-methyltransferase 3-like
- Rat(309680) DNA (cytosine-5-)-methyltransferase 3-like
- dog(608536) DNA (cytosine-5-)-methyltransferase 3-like
- domestic cat(101091300) DNA (cytosine-5-)-methyltransferase 3-like
- cow(613785) DNA (cytosine-5-)-methyltransferase 3-like
- sheep(101102451) DNA (cytosine-5-)-methyltransferase 3-like
- naked mole-rat(101719207) DNA (cytosine-5-)-methyltransferase 3-like
- domestic guinea pig(100729608) DNA (cytosine-5-)-methyltransferase 3-like
- Horse(100050680) DNA (cytosine-5-)-methyltransferase 3-like
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Antibodies
Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-DNMT3L antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reatividade de espécies
human
Aplicação
immunofluorescence
western blot
western blot
Anti-DNMT3L antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
Anti-DNMT3L, from rabbit,
Reatividade de espécies
mouse
Aplicação
immunocytochemistry
immunofluorescence
western blot
immunofluorescence
western blot
Proteins
Número do produto
Descrição
Espécies
DNMT3A/DNMT3L active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥90% (SDS-PAGE),
Espécies
human
esiRNA
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Descrição
Espécies