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GHRL

ghrelin/obestatin prepropeptide

Sinônimos:
MTLRP
Espécies:
ID UniProtKB:
ID do gene:
  • Human(51738) Summary: This gene encodes ghrelin-obestatin preproprotein, which generates ghrelin and obestatin. Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor and is involved in regulating growth hormone release. Obestatin was initially reported to be an endogenous ligand for the orphan G protein-coupled receptor GPR39 and was involved in satiety and decreased food intake; however, these findings are controversial. Recent reports show that obestatin is involved in inhibiting thirst and anxiety, improving memory, regulating sleep, affecting cell proliferation, and increasing the secretion of pancreatic juice enzymes. Alternative promoters and alternative splicing result in multiple transcript variants, some of which encode different protein isoforms and some of which do not encode a protein but may regulate the ghrelin-obestatin preproprotein expression. In addition, antisense transcripts for this gene have been identified and may also function in regulation of the ghrelin-obestatin preproprotein expression. [provided by RefSeq, Oct 2008]
  • Mouse(58991) ghrelin
  • Rat(59301) ghrelin/obestatin prepropeptide
  • Zebrafish(798613) ghrelin/obestatin preprohormone
  • chicken(408185) ghrelin/obestatin prepropeptide
  • naked mole-rat(101710248) ghrelin/obestatin prepropeptide
  • Horse(100058008) ghrelin/obestatin prepropeptide
  • domestic guinea pig(100717245) ghrelin/obestatin prepropeptide
  • sheep(442996) ghrelin/obestatin prepropeptide
  • Goat(100861189) ghrelin/obestatin prepropeptide
  • dog(403587) ghrelin/obestatin prepropeptide
  • domestic cat(493844) ghrelin/obestatin prepropeptide
  • cow(281192) ghrelin/obestatin prepropeptide

Custom & Knockdown Gene Products

ELISA

Número do produto
Descrição
Espécies
Obestatin EIA Kit, for serum, plasma, culture supernatant and cell lysates,
Espécies
human

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-Ghrelin Antibody, clone 1ML-1D7, ascites fluid, clone 1ML-1D7, from mouse,
Reatividade de espécies
human, mouse
Aplicação
immunocytochemistry
western blot
Anti-GHRL antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
western blot
Monoclonal Anti-GHRL antibody produced in mouse, clone 4B8, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
ELISA
immunohistochemistry

western blot
Anti-Obestatin Antibody, Chemicon®, from chicken,
Reatividade de espécies
mouse, rat
Aplicação
ELISA

Proteins

Número do produto
Descrição
Espécies
Ghrelin rat, lyophilized powder,
Espécies
rat