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Merck

GRM7

glutamate receptor, metabotropic 7

Sinônimos:
GLUR7, GPRC1G, MGLU7, MGLUR7
Espécies:
Human GRM7 (2917), Mouse Grm7 (108073), Rat Grm7 (81672), Zebrafish grm7 (564461), chicken GRM7 (416112), Horse GRM7 (100052696), domestic cat GRM7 (101090088), Domestic Rabbit GRM7 (100343810), cow GRM7 (535362), dog GRM7 (484674)
ID UniProtKB:
Q14831, Q8NFS2, Q8NFS3, Q8NFS4
ID do gene:
  • Human(2917) Summary: L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]
  • Mouse(108073) glutamate receptor, metabotropic 7
  • Rat(81672) glutamate receptor, metabotropic 7
  • Zebrafish(564461) glutamate receptor, metabotropic 7
  • chicken(416112) glutamate receptor, metabotropic 7
  • Horse(100052696) glutamate receptor, metabotropic 7
  • domestic cat(101090088) glutamate receptor, metabotropic 7
  • Domestic Rabbit(100343810) glutamate receptor, metabotropic 7
  • cow(535362) glutamate receptor, metabotropic 7
  • dog(484674) glutamate receptor, metabotropic 7

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Small Molecule - Agonist

Número do produto
Descrição
Espécies
P0878
O-Phospho-L-serine, ,
Espécies
human
A155
trans-(±)-ACPD monohydrate, solid, ≥97% (NMR),
Espécies
human
A7929
L-(+)-2-Amino-4-phosphonobutyric acid, optical purity optical purity: ≥95% (HPLC, Marfey′s reagent),
Espécies
rat, human
G1251
L-Glutamic acid, ReagentPlus®, ≥99% (HPLC),
Espécies
rat, human
G8415
L-Glutamic acid, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Espécies
rat, human

Small Molecule - Antagonist

Número do produto
Descrição
Espécies
A4910
DL-2-Amino-3-phosphonopropionic acid, ,
Espécies
human
G1251
L-Glutamic acid, ReagentPlus®, ≥99% (HPLC),
Espécies
rat, human
G8415
L-Glutamic acid, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Espécies
rat, human
49449
L-Glutamic acid, BioUltra, ≥99.5% (NT),
Espécies
rat, human
W328502
L-Glutamic acid, FCC,
Espécies
rat, human

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
07-239
Anti-mGluR7 Antibody, Upstate®, from rabbit,
Reatividade de espécies
rat
Aplicação
western blot
SAB4501326
Anti-GRM7 antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
immunofluorescence
western blot
SAB4501325
Anti-MGLUR7 antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
immunohistochemistry
western blot
AB9213
Anti-Metabotropic Glutamate Receptor 7 Antibody, Chemicon®, from rabbit,
Reatividade de espécies
human
Aplicação
immunohistochemistry
western blot

Small Molecule - Mixed Agonist/Antagonist

Número do produto
Descrição
Espécies
A7929
L-(+)-2-Amino-4-phosphonobutyric acid, optical purity optical purity: ≥95% (HPLC, Marfey′s reagent),
Espécies
rat, human
G1251
L-Glutamic acid, ReagentPlus®, ≥99% (HPLC),
Espécies
rat, human
G8415
L-Glutamic acid, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Espécies
rat, human
49449
L-Glutamic acid, BioUltra, ≥99.5% (NT),
Espécies
rat, human
W328502
L-Glutamic acid, FCC,
Espécies
rat, human

esiRNA

Número do produto
Descrição
Espécies
EMNC009781
MISSION® esiRNA, targeting mouse Ak032068,
Espécies
mouse
EHU068401
MISSION® esiRNA, targeting human GRM7,
Espécies
human