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Merck

NEFL

neurofilament, light polypeptide

Sinônimos:
CMT1F, CMT2E, NF-L, NF68, NFL
Espécies:
ID UniProtKB:
ID do gene:
  • Human(4747) Summary: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008]
  • Mouse(18039) neurofilament, light polypeptide
  • Rat(83613) neurofilament, light polypeptide
  • chicken(419528) neurofilament, light polypeptide
  • sheep(101119539) neurofilament, light polypeptide
  • cow(281348) neurofilament, light polypeptide
  • dog(477378) neurofilament, light polypeptide
  • naked mole-rat(101704332) neurofilament, light polypeptide
  • domestic cat(101081039) neurofilament, light polypeptide
  • domestic guinea pig(100731797) neurofilament, light polypeptide

Custom & Knockdown Gene Products

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-Neurofilament L Antibody, serum, Chemicon®,
Reatividade de espécies
bovine, canine, feline, human, mouse, pig, rat
Aplicação
immunocytochemistry
immunohistochemistry

western blot
Monoclonal Anti-Neurofilament 68 antibody produced in mouse, clone NR4, ascites fluid,
Reatividade de espécies
chicken, human, pig, rat
Aplicação
immunohistochemistry
microarray

western blot
Anti-Neurofilament 70 kDa Antibody, clone DA2, culture supernatant, clone DA2, Chemicon®,
Reatividade de espécies
bovine, human, mouse, pig, rat
Aplicação
immunocytochemistry
immunohistochemistry

western blot
Anti-Neurofilament L Antibody, clone 1E13 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reatividade de espécies
human
Aplicação
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-phospho-NFL (Ser473) Antibody, clone 4F8, clone 4F8, from mouse,
Reatividade de espécies
bovine, human, mouse, porcine, rat, rhesus macaque
Aplicação
immunohistochemistry
western blot

Proteins

Número do produto
Descrição
Espécies
Neurofilament 70 kDa, porcine, ,
Espécies

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human NEFL,
Espécies
human