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Merck

PTS

6-pyruvoyltetrahydropterin synthase

Sinônimos:
PTPS
Espécies:
ID UniProtKB:
ID do gene:
  • Human(5805) Summary: The enzyme encoded by this gene catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin, also known as BH(4), is an essential cofactor and regulator of various enzyme activities, including enzymes involved in serotonin biosynthesis and NO synthase activity. Mutations in this gene result in hyperphenylalaninemia. [provided by RefSeq, Oct 2008]
  • Mouse(19286) 6-pyruvoyl-tetrahydropterin synthase
  • Rat(29498) 6-pyruvoyl-tetrahydropterin synthase
  • fruit fly(252458) ponte thermosensible
  • Zebrafish(100073330) 6-pyruvoyltetrahydropterin synthase
  • chicken(374144) 6-pyruvoyltetrahydropterin synthase
  • dog(611326) 6-pyruvoyltetrahydropterin synthase
  • domestic cat(101096347) 6-pyruvoyltetrahydropterin synthase
  • cow(506860) 6-pyruvoyltetrahydropterin synthase
  • sheep(101108950) 6-pyruvoyltetrahydropterin synthase
  • domestic guinea pig(100733894) 6-pyruvoyltetrahydropterin synthase
  • naked mole-rat(101705212) 6-pyruvoyltetrahydropterin synthase

Custom & Knockdown Gene Products

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-phospho-PTS (Ser19) Antibody, clone 24GB800, Rabbit Monoclonal, clone 24GB800, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reatividade de espécies
human, rat
Aplicação
flow cytometry
immunofluorescence

western blot

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human PTS,
Espécies
human
MISSION® esiRNA, targeting mouse Pts,
Espécies
mouse