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Merck

TP53

tumor protein p53

Sinônimos:
BCC7, LFS1, P53, TRP53
Espécies:
Human TP53 (7157), Rat Tp53 (24842), Domestic Rabbit TP53 (100009292), domestic guinea pig Tp53 (100379269), sheep TP53 (443421), cow TP53 (281542), Zebrafish tp53 (30590), naked mole-rat Tp53 (101701769), dog TP53 (403869), chicken TP53 (396200) ...Mais
ID UniProtKB:
P04637, Q15086, Q15087, Q15088, Q16535, Q16807, Q16808, Q16809
ID do gene:
  • Human(7157) Summary: This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013]
  • Rat(24842) tumor protein p53
  • Domestic Rabbit(100009292) tumor protein p53
  • domestic guinea pig(100379269) tumor protein p53
  • sheep(443421) tumor protein p53
  • cow(281542) tumor protein p53
  • Zebrafish(30590) tumor protein p53
  • naked mole-rat(101701769) tumor protein p53
  • dog(403869) tumor protein p53
  • chicken(396200) tumor protein p53
  • Horse(100062044) tumor protein p53
  • domestic cat(493847) tumor protein p53

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ELISA

Número do produto
Descrição
Espécies
RAB0500
Human p53 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Espécies
human
RAB0910
Rat Tp53 / Cellular Tumor Antigen p53 ELISA Kit, ,
Espécies
rat

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
MABE339
Anti-p53 (wild type) Antibody, clone PAb1620, clone Pab1620, from mouse,
Reatividade de espécies
human, mouse
Aplicação
immunohistochemistry
western blot
OP43
Anti-p53 (Ab-6) (Pantropic) Mouse mAb (DO-1), liquid, clone DO-1, Calbiochem®,
Reatividade de espécies
feline, human
Aplicação
OP29
Anti-p53 (Ab-3) (Mutant) Mouse mAb (PAb240), liquid, clone PAb240, Calbiochem®,
Reatividade de espécies
bovine, chicken, hamster, human, mouse, rat
Aplicação
P6874
Anti-p53 antibody, Mouse monoclonal, clone DO-1, purified from hybridoma cell culture,
Reatividade de espécies
human
Aplicação
ELISA
flow cytometry
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
microarray
western blot
OP33
Anti-p53 (Ab-5) (Wild type) Mouse mAb (PAb1620), liquid, clone PAb1620, Calbiochem®,
Reatividade de espécies
bovine, human, mouse, primate, rat
Aplicação

Cell Lines

Número do produto
Descrição
Espécies
CLLS1049
MCF10A CELLS TP53 (-/-), ,
Espécies
human
CLLS1007
SW48 Cells TP53 -/-, ,
Espécies
human
CLLS1127
DLD1 Cells TP53 -/-, ,
Espécies
human

Proteins

Número do produto
Descrição
Espécies
23-034-M
p53 Protein, 10 µg, Full length, recombinant human p53. N-terminal c-Myc, 6His-tagged. For use in Enzyme Assays. Functions as a substrate in ubiquitination assays.,
Espécies
14-865
p53-GST (recombinant protein), ,
Espécies
P6249
p53 human, recombinant, expressed in E. coli, buffered aqueous glycerol solution,
Espécies
human
P6374
p53 human, recombinant, expressed in baculovirus infected Sf21 cells,
Espécies
human
SRP2108
p53 (1-81), mutant, GST tagged human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
EHU123221
MISSION® esiRNA, targeting human TP53,
Espécies
human