TYK2
tyrosine kinase 2
Sinônimos:
JTK1
Espécies:
Human TYK2 (7297), Mouse Tyk2 (54721), Rat Tyk2 (100361294), domestic cat TYK2 (101090171), dog TYK2 (476714), chicken TYK2 (430113), Zebrafish tyk2 (100536675), cow TYK2 (512484), domestic guinea pig Tyk2 (100715734), sheep TYK2 (101117248)
ID UniProtKB:
ID do gene:
- Human(7297) Summary: This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq, Jul 2008]
- Mouse(54721) tyrosine kinase 2
- Rat(100361294) tyrosine kinase 2
- domestic cat(101090171) tyrosine kinase 2
- dog(476714) tyrosine kinase 2
- chicken(430113) tyrosine kinase 2
- Zebrafish(100536675) tyrosine kinase 2
- cow(512484) tyrosine kinase 2
- domestic guinea pig(100715734) tyrosine kinase 2
- sheep(101117248) tyrosine kinase 2
- naked mole-rat(101715782) tyrosine kinase 2
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Número do produto
Descrição
Espécies
Antibodies
Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-TYK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-TYK2 Antibody, clone 2H22 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reatividade de espécies
bovine, human, monkey, porcine
Aplicação
affinity binding assay
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Phospho-Tyk2-Y1054/1055 antibody produced in rabbit, ,
Reatividade de espécies
human, mouse, rat
Aplicação
immunohistochemistry
western blot
western blot
Anti-phospho-TYK2 (pTyr1054) antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
western blot
Anti-phospho-Tyk2 (pTyr1054/1055) antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
western blot
Small Molecule - Inhibitor
Número do produto
Descrição
Espécies
esiRNA
Número do produto
Descrição
Espécies