142824

Sigma-Aldrich

1-Methyl-1-cyclohexanecarboxylic acid

99%

Fórmula linear:
CH3C6H10CO2H
Número CAS:
Peso molecular:
142.20
Número EC:
Número MDL:
ID de substância PubChem:
NACRES:
NA.22

teor

99%

pb

234 °C (lit.)

pf

36-39 °C (lit.)

SMILES string

CC1(CCCCC1)C(O)=O

InChI

1S/C8H14O2/c1-8(7(9)10)5-3-2-4-6-8/h2-6H2,1H3,(H,9,10)

InChI key

REHQLKUNRPCYEW-UHFFFAOYSA-N

Categorias relacionadas

Descrição geral

1-Methyl-1-cyclohexanecarboxylic acid is the structural analog of valproic acid and its pharmacokinetic action has been studied in female Sprague-Dawley rats.

Aplicação

1-Methyl-1-cyclohexanecarboxylic acid was used as internal standard during the determination of valproic acid metabolites.

Embalagem

10 g in glass bottle

Ações bioquímicas/fisiológicas

1-Methyl-1-cyclohexanecarboxylic acid is an anticonvulsant drug and causes maturation of murine neuroblastoma cells in vitro.

storage_class_code

13 - Non Combustible Solids

WGK Alemanha

WGK 3

Ponto de fulgor (ºF)

213.8 °F - closed cup

Ponto de fulgor (ºC)

101.00 °C - closed cup

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificado de análise

Certificado de origem

P Benoit et al.
Neuropharmacology, 21(12), 1239-1244 (1982-12-01)
The effect of an anticonvulsant compound (Simiand, Ferrandes, Lacolle and Eymard, 1979), 1-methyl cyclohexane carboxylic acid (CCA), upon the electrical activity of Purkinje cells (PCs) was studied in the cerebellar cortex of the rat in vivo. Cyclohexane carboxylic acid (200-400...
J C Larcher et al.
Experimental cell research, 203(1), 72-79 (1992-11-01)
Adriamycin, an anticancer agent acting on topoisomerase II, promotes the arrest of cell division and neurite extension in a "neurite-minus" murine neuroblastoma cell line, N1A-103. This morphological differentiation is accompanied by a blockade in the S phase of the cell...
J C Larcher et al.
Oncogene, 6(4), 633-638 (1991-04-01)
Using clones N1E-115 and N1A-103 from mouse neuroblastoma C1300, a comparative analysis of c- and N-myc gene expression was undertaken both in proliferating cells and in cultures exposed to conditions which induce differentiation. Under the latter conditions, while N1E-115 cells...
A J Sadeque et al.
The Journal of pharmacology and experimental therapeutics, 283(2), 698-703 (1997-11-14)
Cytochrome P450-dependent desaturation of the anticonvulsant drug valproic acid (VPA) results in formation of the hepatotoxin, 4-ene-VPA. Polytherapy with other anticonvulsants which are known P450 inducers increases the flux through this bioactivation pathway. The aim of the present study was...
Effects on the cytoskeleton of a new inducer of the neuroblastoma morphological differentiation.
M M Portier et al.
Biochemical and biophysical research communications, 96(4), 1610-1618 (1980-10-31)

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica