15404

Sigma-Aldrich

N-Boc-1,4-butanediamine

≥97.0% (GC/NT)

Sinônimo(s):
N-Boc-1,4-diaminobutane, tert-Butyl N-(4-aminobutyl)carbamate
Fórmula linear:
(CH3)3COCONH(CH2)4NH2
Número CAS:
Peso molecular:
188.27
Beilstein/REAXYS Number:
1937878
Número MDL:
ID de substância PubChem:

Nível de qualidade

100

teor

≥97.0% (GC/NT)

reaction suitability

reagent type: cross-linking reagent
reagent type: spacer

índice de refração

n20/D 1.460

densidade

0.984 g/mL at 20 °C (lit.)

SMILES string

CC(C)(C)OC(=O)NCCCCN

InChI

1S/C9H20N2O2/c1-9(2,3)13-8(12)11-7-5-4-6-10/h4-7,10H2,1-3H3,(H,11,12)

InChI key

ZFQWJXFJJZUVPI-UHFFFAOYSA-N

Categorias relacionadas

Embalagem

1, 5 mL in glass bottle

Outras notas

Preparation of pharmacologically active compounds. Preparation of spermidine analogues. Introduction of a C4-spacer.

Pictogramas

Corrosion

Palavra indicadora

Danger

Frases de perigo

Declarações de precaução

Equipamento de proteção individual

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

RIDADR

UN 2735PSN2 8 / PGIII

WGK Alemanha

WGK 3

Ponto de fulgor (ºF)

228.2 °F - closed cup

Ponto de fulgor (ºC)

109.0 °C - closed cup

Certificado de análise
Certificado de origem
Y Shai et al.
Biochemistry, 28(11), 4801-4806 (1989-05-30)
In the present study we synthesize 18F-labeled insulin of high specific radioactivity. A new prosthetic group methodology, in which [18F]fluoride displaces a bromide group of 4-(bromomethyl)-benzoylamine intermediates, was used. The 4-(fluoromethyl)benzoyl product was chemically stable. 18F-Labeled insulin retains the essential...
Regina Holm et al.
Macromolecular rapid communications, 36(23), 2083-2091 (2015-09-08)
In this work, the synthesis of polypeptoid-block-polypeptide copolymers (block copolypept(o)ides) based on bifunctional initiators is described, which introduces a distinct chemical entity at the connection between both blocks. With a view towards redox-sensitive block copolypept(o)ides, a cystamine-based initiator was used...
Hongyan Guo et al.
Journal of medicinal chemistry, 45(10), 2056-2063 (2002-05-03)
Several iron chelators containing alpha,beta-unsaturated hydroxamic acid motifs appended to a citric acid platform were synthesized. Mycobacterium paratuberculosis was then challenged to grow in the presence of a panel of siderophores (mycobactin J, deferrioxamine B, acinetoferrin, and nannochelin A) and...
H.H. Wassermann et al
Tetrahedron, 58, 7177-7177 (2002)
Regina Holm et al.
Biomacromolecules, 20(1), 375-388 (2018-11-27)
The size control of nanomedicines for tumor diagnosis and therapy is of high importance, since it enables or disables deep and sufficient tumor penetration. Amphiphilic star-shaped block copolypept(o)ides offer substantial promise to precisely adjust the hydrophobic core and the hydrophilic...
Artigos
Mono-Boc-protected diamines are versatile building blocks for chemical synthesis. Their production is a lot more challenging than the simple reaction scheme might imply, because the Boc-anhydride reagent cannot differentiate between the two identical amino moieties in the substrate.
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