329878

Sigma-Aldrich

Water-18O

(for PET), 97 atom % 18O

Sinônimo(s):
18O Water
Fórmula linear:
H218O
Número CAS:
Peso molecular:
20.02
Número MDL:
ID de substância PubChem:
NACRES:
NA.12

Nível de qualidade

200

descrição

Normalized with respect to hydrogen

pureza isotópica

97 atom % 18O

aplicação(ões)

PET imaging: suitable

pb

100 °C (lit.)

pf

0 °C (lit.)

densidade

1.11 g/mL at 20 °C (lit.)

compatibilidade

(for PET)

alteração de massa

M+2

SMILES string

[18OH2]

InChI

1S/H2O/h1H2/i1+2

InChI key

XLYOFNOQVPJJNP-NJFSPNSNSA-N

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Aplicação

Water-18O is an isotopically modified water, which is appropriate for PET applications.
It can also be used:
  • In paleoclimatology, hydrology, and plant ecology to determine soil stable oxygen isotope analysis of plant cellulose using δ18O.
  • To determine the diffusion of moisture into crystals using secondary ion mass spectrometry (SIMS).

Embalagem

250 mg in serum bottle
1 g in serum bottle
This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.
Packaged in septum-sealed serum bottles.

storage_class_code

10 - Combustible liquids

WGK Alemanha

nwg

Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Certificado de análise

Certificado de origem

Christian Berk et al.
FEBS letters, 595(2), 230-240 (2020-10-29)
Identifying the targetome of a microRNA is key for understanding its functions. Cross-linking and immunoprecipitation (CLIP) methods capture native miRNA-mRNA interactions in cells. Some of these methods yield small amounts of chimeric miRNA-mRNA sequences via ligation of 5'-phosphorylated RNAs produced...
Xueyan Cao et al.
Food chemistry, 276, 266-273 (2018-11-10)
Milk glycoproteins are crucial nutrients with a variety of functions. However, whey N-glycoproteomes in human and bovine milks have not been characterized during lactation. Herein, using lectin enrichment and liquid chromatography tandem mass spectrometry, 68, 58, 100, and 98 N-glycoproteins...
Diffusion of Water Species in Yttria-Stabilized Zirconia
Duong T, et al.
Journal of the American Chemical Society, 92(11), 2731-2737 (2009)
Separating soil and leaf water 18O isotopic signals in plant stem cellulose
Sternberg, Leonel da Silveira Lobo and Anderson, William T and Morrison, Kanema
Geochimica et Cosmochimica Acta, 67(14), 2561-2566 (2003)
Andrew J Thompson et al.
Cell host & microbe, 27(5), 725-735 (2020-04-17)
Hemagglutinins (HAs) from human influenza viruses adapt to bind α2-6-linked sialosides, overcoming a receptor-defined species barrier distinct from the α2-3 specificity of avian virus progenitors. Additionally, human-adapted HAs gain glycosylation sites over time, although their biological function is poorly defined....
Artigos
By first labeling molecular oxygen and then body water with 18O in a rat, Lifson measured the 18O abundance in expired CO2 and found the oxygens in CO2 exchanged with the oxygen in water. Indeed, these two oxygen containing species were in rapid isotopic equilibrium due to the actions of what we now know is carbonic anhydrase (Lifson, 1966)
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Conteúdo relacionado
Labeled isotopes used as target materials in imaging have provided insights into the various mechanisms of human physiology and have lead to treatments for diseases. Water-18O is used for the production of 18F radionuclides, such as 18FDG (Fluoro-deoxyglucose). 18FDG used in PET and with other imaging technologies, such as CT/SPECT, has led to the diagnosis and treatment of a wide range of diseases, including lung, liver, and brain tumors, epilepsy, and Alzheimer’s.
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