440191

Hexamethyldisilazane

reagent grade, ≥99%

• Sinônimo(s): Bis(trimethylsilyl)amine, HMDS
• Fórmula linear: (CH₃)₃SiNHSi(CH₃)₃
• CAS Number: 999-97-3
• Peso molecular: 161.39
• Beilstein: 635752
• Número CE: 213-668-5
• Número MDL: MFCD00008259
• Código UNSPSC: 12352103
• ID de substância PubChem: 24867576
• NACRES: NA.23

Propriedades

• grau: reagent grade
• Ensaio: ≥99%
• Formulário: liquid
• índice de refração: n20/D 1.407 (lit.)
• p.e.: 125 °C (lit.)
• cadeia de caracteres SMILES: C[Si](C)(C)N[Si](C)(C)C
• InChI: 1S/C6H19NSi2/c1-8(2,3)7-9(4,5)6/h7H,1-6H3
• chave InChI: FFUAGWLWBBFQJT-UHFFFAOYSA-N

Descrição

Descrição geral

Hexamethyldisilane (HMDS) is a stable and effectivereagent for trimethylsilylation of hydrogen-labile substrates such as alcohols,amines, and carboxylic acids. It is commonly used for the protection of sensitivefunctional groups during chemical synthesis. Owing to its low cost, high vapor pressure, and safety, itis widely used as a precursor in chemical vapor deposition(CVD) reactions.

Aplicação

Hexamethyldisilane (HMDS) can be used:

• As a silylating agent in the trimethylsilylation of alcohols under nearly neutral reaction conditions.
• To control the molecular weights of polypeptides during ring-opening polymerization of α-amino acid N-carboxyanhydrides.
• To fabricate silicon carbonitride thin films by plasma-enhanced CVD.
• For specimen preparation for scanning electron microscopy and the preparation of trimethylsilyl ethers from hydroxy compounds.

Características e benefícios

• High chemicalstability and low molecular weight
• Nontoxic andcost-effective reagent
• Ammonia is theonly byproduct generated during silylation
• Silylationreaction using HDMS is nearly neutral and does not need any precaution

Informações de segurança

• Pictogramas: GHS02,GHS06
• Palavra indicadora: Danger
• Frases de perigo: H225,H302 + H332,H311,H412
• Declarações de precaução: P210 - P273 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312
• Classificações de perigo: Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Flam. Liq. 2
• Código de classe de armazenamento: 3 - Flammable liquids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): 52.5 °F - closed cup
• Ponto de fulgor (°C): 11.4 °C - closed cup
• Equipamento de proteção individual: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter