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440191

Sigma-Aldrich

Hexamethyldisilazane

reagent grade, ≥99%

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Sinônimo(s):
Bis(trimethylsilyl)amine, HMDS
Fórmula linear:
(CH3)3SiNHSi(CH3)3
Número CAS:
999-97-3
Peso molecular:
161.39
Beilstein/REAXYS Number:
635752
Número EC:
213-668-5
Número MDL:
MFCD00008259
ID de substância PubChem:
24867576
NACRES:
NA.23

Nível de qualidade

300

grau

reagent grade

teor

≥99%

forma

liquid

índice de refração

n20/D 1.407 (lit.)

pb

125 °C (lit.)

SMILES string

C[Si](C)(C)N[Si](C)(C)C

InChI

1S/C6H19NSi2/c1-8(2,3)7-9(4,5)6/h7H,1-6H3

InChI key

FFUAGWLWBBFQJT-UHFFFAOYSA-N

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Descrição geral

Hexamethyldisilazane (HMDS) is used to trimethylsilylate alcohols, amines, thiols. HMDS can also be used for the preparation of trimethylsilyl ethers from hydroxy compounds.

Aplicação

HMDS is used for specimen preparation for scanning electron microscopy.

Embalagem

1 L in Sure/Seal™
100 mL in Sure/Seal™

Palavra indicadora

Danger

hazcat

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Flam. Liq. 2 - Skin Corr. 1B

storage_class_code

3 - Flammable liquids

WGK Alemanha

WGK 2

Ponto de fulgor (ºF)

52.5 °F - closed cup

Ponto de fulgor (ºC)

11.4 °C - closed cup

Equipamento de proteção individual

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Certificado de análise

Certificado de origem

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Critical point drying (CPD) is a common method of drying biological specimens for scanning electron microscopy (SEM). Drying by evaporation of hexamethyldisilazane (HMDS) has been described as a good alternative. This method, however, is infrequently used. Therefore, we reassessed HMDS...
Rapid and highly efficient trimethylsilylation of alcohols and phenols
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