605166

Sigma-Aldrich

L-Glutamine-13C5

98 atom % 13C, 95% (CP)

Sinônimo(s):
(S)-2,5-Diamino-5-oxopentanoic acid-13C5, 13C Labeled glutamine, L-Glutamic acid 5-amide-13C5, L-Glutamine-ul-13C
Fórmula linear:
H2N13CO(13CH2)213CH(NH2)13CO2H
Número CAS:
Peso molecular:
151.11
Número MDL:
ID de substância PubChem:
NACRES:
NA.12

pureza isotópica

98 atom % 13C

Nível de qualidade

200

teor

95% (CP)

atividade óptica

[α]25/D +33.0°, c = 2 in 5 M HCl

pf

185 °C (dec.) (lit.)

alteração de massa

M+5

SMILES string

[H][13C@](N)([13CH2][13CH2][13C](N)=O)[13C](O)=O

InChI

1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m0/s1/i1+1,2+1,3+1,4+1,5+1

InChI key

ZDXPYRJPNDTMRX-WIAREEORSA-N

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Descrição geral

L-Glutamine plays an important role in nucleotide synthesis. It functions as a critical fuel for lymphocytes and gut epithelial cells. L-Glutamine is essential in the endogenous synthesis of glutathione. It is an essential amino acid, which is useful in stressful conditions. L-Glutamine is involved in protein synthesis, wound healing, regulating acid-base balance, cellular differentiation, acts as an energy source and modulates the immune system.

Aplicação

L-Glutamine-13C5 has been used for gas chromatography-mass spectrometry (GC-MS) of RAW264.7 cells. It has also been used for metabolomics analysis in p53Mut-parental mesenchymal stem cells (MSCs) or p53Mut-MSC-tumor lines.

Embalagem

100, 500 mg in glass bottle
This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

storage_class_code

13 - Non Combustible Solids

WGK Alemanha

WGK 3

Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Certificado de análise

Certificado de origem

Kyung-Hee Kim et al.
Oncotarget, 8(68), 112598-112609 (2018-01-20)
We searched for metabolic biomarkers that may predict the prognosis of patients with intrahepatic cholangiocarcinoma (IHCC). To this end, a total of 237 serum samples were obtained from IHCC patients (
Metabolism and Nutrition for the Surgical Patient, Part II, An Issue of Surgical Clinics - E-Book (2011)
TiO2 nanoparticles cause mitochondrial dysfunction, activate inflammatory responses, and attenuate phagocytosis in macrophages: A proteomic and metabolomic insight
Chen Q, et al.
Redox Biology, 15, 266-276 (2018)
Surgical Critical Care, An Issue of Surgical Clinics - E-Book (2012)
Mutant p53-dependent mitochondrial metabolic alterations in a mesenchymal stem cell-based model of progressive malignancy
Lonetto G, et al.
Cell Death and Differentiation, 1-1 (2018)
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