900285

MCAT-53^™

• Synonym(s): Ru₂Cl₂(p-cymene) (HCOO)₂ • HCOONa, Ru₂Cl₂(p-cymene) (HCOO)₃Na, Sodium η-6-p-cymene dichloro diruthenium (II, III) triformato complex
• Empirical Formula (Hill Notation): C₁₃H₁₇Cl₂NaO₆Ru₂
• Molecular Weight: 565.31
• ID de substância PubChem: 329769798
• NACRES: NA.22

Properties

• forma: powder
• Nível de qualidade: 100
• reaction suitability: core: ruthenium; reaction type: Cross Couplings; reagent type: catalyst; reaction type: C-H Activation
• características do produto alternativo mais ecológico: Less Hazardous Chemical Syntheses; Designing Safer Chemicals; Catalysis; Inherently Safer Chemistry for Accident Prevention; Learn more about the Principles of Green Chemistry.
• pf: 247.8 °C
• categoria alternativa mais ecológica: Aligned
• temperatura de armazenamento: 2-8°C
• SMILES string: C[Ru]OC([H])=O.[Ru]OC([H])=O.ClC.CC.CC1=CC=C(C(C)C)C=C1.COC([H])=O.Cl.[Na]
• InChI: 1S/C10H14.3CH2O2.2ClH.Na.2Ru.H/c1-8(2)10-6-4-9(3)5-7-10;3*2-1-3;;;;;;/h4-8H,1-3H3;3*1H,(H,2,3);2*1H;;;;/q;;;;;;;+2;+3;/p-5
• InChI key: QVXXTDGUSONXKR-UHFFFAOYSA-I

Description

Descrição geral

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product has been enhanced for catalytic efficiency. Click here for more information.

Aplicação

MCAT-53 is a recyclable ruthenium-containing catalyst for C–C coupling reactions in aqueous conditions. In contrast to Pd-catalyzed reactions, MCAT-53 achieves C–H-activated C–C coupling in water under ligand-free conditions, requiring no co-solvent, surfactant, or additional steps for activation. Bench- and air-stable, MCAT-53 will find wide utility in cost-effective and greener alternatives in pharmaceutical and manufacturing processes. This water-friendly catalyst is offered in collaboration with Chicago Discovery Solutions.
The catalyst has been successfully employed to synthesize a key intermediate of anacetrapib as a single regioisomer.

Outras notas

Arene Ruthenium Catalyst MCAT-53 for the Synthesis of Hetero-biaryl Compounds in Water through Aromatic C-H bond Activation

MCAT-53^™: A Green Ruthenium Catalyst for Cross-Coupling & C–H Activation

Informações legais

MCAT-53 is a trademark of Chicago Discovery Solutions LLC

Safety Information

• Código de classe de armazenamento: 11 - Combustible Solids
• Ponto de fulgor (ºF): Not applicable
• Ponto de fulgor (ºC): Not applicable