KITALYSIS-BOR

KitAlysis^™ High-Throughput Miyaura Borylation Reaction Screening Kit-Pack of 2

Properties

• reaction suitability: reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Cross Couplings; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling; reagent type: catalyst; core: palladium
• grupo funcional: phosphine

Description

Aplicação

Screening kit for Miyaura borylation reaction. Step-by-step user guides and a downloadable experimental excel sheets are provided in the below hyperlinks.
Step-by-Step Guide for Miyaura Borylation Reaction Screening Kit
Downloadable Experiment excel sheets

Each kit contains 2 customizable screening sets that include the following components:

• 6 x 4 pre-weighed catalysts in glass vials loaded with stir bars and topped with cap mat.
• 4 x 4 mL reaction vials with pre-weighed KOAc
• Bis(pinacolato)diboron (473294), tetrahydroxydiboron (754242), and pinacol (221171)
• 1 (2 mL) ampule each of toluene, THF, n-butanol, DMA, MeOH, MeCN, ethylene glycol and DIPEA.
• 1 NEW KitAlysis 24-Well Reaction Block Replacement Film.
• 4 stir bars for substrate stock solution vials.
• 1 internal standard.

Monitor reaction progress via TLC-MS by following this protocol

Best when used with KitAlysis Benchtop Inertion Box and 24-well Reaction Block (sold separately).

Características e benefícios

• Designed and tested by synthetic chemists.
• Easily run 24-microscale reactions in parallel.
• 10 μmol reactions with 1 μmol catalyst, 3 equiv. base, 0.1 M concentration.
• Customizable Excel Template for quick calculations and easy incorporation into electronic laboratory notebooks.

Informações legais

KitAlysis is a trademark of Sigma-Aldrich Co. LLC

Kit Components Also Available Separately

• 764175 P(Cy₃) Pd G3, 97%
• 791733 Potassium acetate, anhydrous, free-flowing, Redi-Dri^™, ACS reagent, ≥99.0%
• 804274 XPhos Pd G4, 95%
• 804282 SPhos Pd G4
• 804290 RuPhos Pd G4
• 804975 DTBPF-Pd-G3
• 900349 cataCXium Pd G4
900522 Toluene, anhydrous, ZerO₂^®, 99.8%
900631 Ethylene glycol, anhydrous, ZerO₂^®, 99.8%
900634 N,N-Dimethylacetamide, anhydrous, ZerO₂^®, 99.8%
900636 Tetrahydrofuran, anhydrous, inhibitor-free, ZerO₂^®, ≥99.9%
900639 1-Butanol, anhydrous, ZerO₂^®, 99.8%
900641 Methanol, anhydrous, ZerO₂^®, 99.8%
900644 Acetonitrile, anhydrous, ZerO₂^®, 99.8%
900690 N,N-Diisopropylethylamine, purified by redistillation, ZerO₂^®, 99.5%
221171 Pinacol, 98%
473294 Bis(pinacolato)diboron, 99%
754242 Tetrahydroxydiboron, 95%
B34656 Biphenyl, ReagentPlus^®, 99.5%
Z118850 Spinbar^® magnetic stirring fleas, red, L 10 mm, diam. 3 mm
Z742110 KitAlysis^™ 24-well reaction block replacement film

See All (21)

Safety Information

• Pictogramas: GHS02,GHS05,GHS06,GHS08,GHS09
• Palavra indicadora: Danger
• Frases de perigo: H225 - H301 + H311 + H331 - H315 - H318 - H335 - H336 - H351 - H360D - H370 - H373 - H410
• Declarações de precaução: P210 - P273 - P280 - P301 + P310 - P303 + P361 + P353 - P305 + P351 + P338
• Classificações de perigo: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Repr. 1B - Skin Irrit. 2 - STOT RE 2 Oral - STOT SE 1
• Órgãos-alvo: Kidney
• Perigos de suplementos: EUH019
• Código de classe de armazenamento: 3 - Flammable liquids
• WGK: WGK 3
• Ponto de fulgor (ºF): 1.4 °F
• Ponto de fulgor (ºC): -17 °C