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Sigma-Aldrich

KitAlysis High-Throughput Miyaura Borylation Reaction Screening Kit-Pack of 2

reaction suitability

reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Cross Couplings
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: catalyst
core: palladium

grupo funcional

phosphine

Aplicação

Screening kit for Miyaura borylation reaction. Step-by-step user guides and a downloadable experimental excel sheets are provided in the below hyperlinks.
Step-by-Step Guide for Miyaura Borylation Reaction Screening Kit
Downloadable Experiment excel sheets

Each kit contains 2 customizable screening sets that include the following components:
  • 6 x 4 pre-weighed catalysts in glass vials loaded with stir bars and topped with cap mat.
  • 4 x 4 mL reaction vials with pre-weighed KOAc
  • Bis(pinacolato)diboron (473294), tetrahydroxydiboron (754242), and pinacol (221171)
  • 1 (2 mL) ampule each of toluene, THF, n-butanol, DMA, MeOH, MeCN, ethylene glycol and DIPEA.
  • 1 NEW KitAlysis 24-Well Reaction Block Replacement Film.
  • 4 stir bars for substrate stock solution vials.
  • 1 internal standard.

Best when used with KitAlysis Benchtop Inertion Box and 24-well Reaction Block (sold separately).

Características e benefícios

  • Designed and tested by synthetic chemists.
  • Easily run 24-microscale reactions in parallel.
  • 10 μmol reactions with 1 μmol catalyst, 3 equiv. base, 0.1 M concentration.
  • Customizable Excel Template for quick calculations and easy incorporation into electronic laboratory notebooks.

Informações legais

KitAlysis is a trademark of Sigma-Aldrich Co. LLC

Componentes do kit também disponíveis separadamente

Nº do produto
Descrição
SDS

  • 764175P(Cy3) Pd G3, 97%

  • 791733Potassium acetate, anhydrous, free-flowing, Redi-Dri, ACS reagent, ≥99.0%

  • 804274XPhos Pd G4, 95%

  • 804282SPhos Pd G4

  • 804290RuPhos Pd G4

  • 804975DTBPF-Pd-G3

  • 900349cataCXium Pd G4

  • 900522Toluene, anhydrous, ZerO2®, 99.8%

  • 900631Ethylene glycol, anhydrous, ZerO2®, 99.8%

  • 900634N,N-Dimethylacetamide, anhydrous, ZerO2®, 99.8%

  • 900636Tetrahydrofuran, anhydrous, inhibitor-free, ZerO2®, ≥99.9%

  • 9006391-Butanol, anhydrous, ZerO2®, 99.8%

  • 900641Methanol, anhydrous, ZerO2®, 99.8%

  • 900644Acetonitrile, anhydrous, ZerO2®, 99.8%

  • 900690N,N-Diisopropylethylamine, purified by redistillation, ZerO2®, 99.5%

  • 221171Pinacol, 98%

  • 473294Bis(pinacolato)diboron, 99%

  • 754242Tetrahydroxydiboron, 95%

  • B34656Biphenyl, ReagentPlus®, 99.5%

  • Z118850Spinbar® magnetic stirring fleas, red, L 10 mm, diam. 3 mm

  • Z742110KitAlysis 24-well reaction block replacement film

Ver tudo (21)

Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Repr. 1B - Skin Irrit. 2 - STOT RE 2 Oral - STOT SE 1

Órgãos-alvo

Kidney

Perigos de suplementos

Código de classe de armazenamento

3 - Flammable liquids

WGK

WGK 3

Ponto de fulgor (ºF)

1.4 °F

Ponto de fulgor (ºC)

-17 °C

Certificado de análise

Certificado de origem

Artigos

KitAlysis™ High-Throughput Screening Platform

KitAlysis High-Throughput Screening Kits provide solution to efficiently identify or optimize suitable catalytic reaction conditions. Chemist can rapidly run 24 unique micro scale reactions in parallel with tailored conditions.

Protocolos

Catalyst Screening followed by TLC-MS for Reaction Progress Analysis using KitAlysis™

Catalyst screening, KitAlysis™ High-Throughput Screening Kits, Thin layer chromatography (TLC), parallel analysis, parallel synthesisigh-Throughput Buchwald-Hartwig Amination Reaction Screening Kit, TLC-MS analysis

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