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840034P

Avanti

16:0-18:1 PS (POPS)

Avanti Research - A Croda Brand

Sinônimo(s):

1-hexadecanoyl-2--(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine (sodium salt); POPS; PS(16:0/18:1(9Z)); 110669

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10 MG

R$ 510,00

25 MG

R$ 793,00

200 MG

R$ 4.053,00

500 MG

R$ 7.581,00

R$ 510,00


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Sobre este item

Fórmula empírica (Notação de Hill):
C40H75NO10PNa
Número CAS:
Peso molecular:
783.99
MDL number:
UNSPSC Code:
51191904
NACRES:
NA.25

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InChI key

RQYKXRYGZHMUSU-JEAFVVATSA-M

SMILES string

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]

description

1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-L-serine (sodium salt)

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (840034P-10mg), pkg of 2 × 100 mg (840034P-200mg), pkg of 5 × 100 mg (840034P-500mg), pkg of 1 × 25 mg (840034P-25mg)

manufacturer/tradename

Avanti Research - A Croda Brand

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

General description

Phosphoserine/phosphatidylserine (PS) is an endogenous phospholipid,[1] that is found in all polyanionic macromolecules.[2]

Application

16:0-18:1 PS (POPS) has been used:
  • in phospholipid mixture for nanodisc preparation[3]
  • in liposome preparation[4]
  • in lipid vesicle preparation for surface plasmon resonance (SPR) analysis[5]

Biochem/physiol Actions

Phosphoserine (PS) can be used as a template for the recognition of cancer antigen 125 (CA 125).[6] It is very essential for healthy nerve cell membranes and myelin.[1] Exogenous PS can be actively absorbed in humans. It has the ability to cross the blood-brain barrier. It plays a key role in the formation of short-term memory, the ability to create new memories, to focus attention, to reason and solve problems and several other cognitive activities. It actively participates in the locomotor functions, like rapid reactions and reflexes.[1]

Packaging

5 mL Clear Glass Sealed Ampule (840034P-10mg)
5 mL Clear Glass Sealed Ampule (840034P-200mg)
5 mL Clear Glass Sealed Ampule (840034P-25mg)
5 mL Clear Glass Sealed Ampule (840034P-500mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Classe de armazenamento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Certificados de análise (COA)

Lot/Batch Number

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Fluorophore Labeling, Nanodisc Reconstitution and Single-molecule Observation of a G Protein-coupled Receptor
Lamichhane R, et al.
Bio-protocol, 7(12) (2017)
Cellular phosphatase activity of C1-Ten/Tensin2 is controlled by Phosphatidylinositol-3, 4, 5-triphosphate binding through the C1-Ten/Tensin2 SH2 domain
Kim E, et al.
Cellular Signalling, 51, 130-138 (2018)
Josef Melcr et al.
Journal of chemical theory and computation, 16(1), 738-748 (2019-11-26)
Phosphatidylserine (PS) lipids are important signaling molecules and the most common negatively charged lipids in eukaryotic membranes. The signaling can be often regulated by calcium, but its interactions with PS headgroups are not fully understood. Classical molecular dynamics (MD) simulations
Examination of the Interaction between a Membrane Active Peptide and Artificial Bilayers by Dual Polarisation Interferometry
Payne JAE, et al.
Bio-protocol, 7(1), e2087-e2087 (2017)
Kari Kusler et al.
The journal of physical chemistry. B, 120(50), 12883-12889 (2016-12-14)
Phosphatidylserine (PS) has previously been found to bind Cu2+ in a ratio of 1 Cu2+ ion per 2 PS lipids to form a complex with an apparent dissociation constant that can be as low as picomolar. While the affinity of

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