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Merck

840051C

Avanti

Egg PC

Avanti Research - A Croda Brand

Sinônimo(s):

Egg PC 99%

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Sobre este item

Número CAS:
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25

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SMILES string

[P](=O)([O-])(OC[C@H](OC(=O)CCCCCCC\C=C/CCCCCCCC)COC(=O)CCCCCCCCCCCCCCC)OCC[N+](C)(C)C

InChI

1S/C42H82NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h20-21,40H,6-19,22-39H2,1-5H3/b21-20-/t40-/m1/s1

InChI key

WTJKGGKOPKCXLL-VYOBOKEXSA-N

description

L-α-phosphatidylcholine (Egg, Chicken), chloroform

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (840051C-25mg), pkg of 2 × 20 mL (840051C-1g), pkg of 2 × 4 mL (840051C-200mg), pkg of 5 × 4 mL (840051C-500mg)

manufacturer/tradename

Avanti Research - A Croda Brand

concentration

10 mg/mL (840051C-25mg), 25 mg/mL (840051C-1g), 25 mg/mL (840051C-200mg), 25 mg/mL (840051C-500mg)

lipid type

phospholipids
phosphoglycerides

shipped in

dry ice

storage temp.

−20°C

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General description

L-α-phosphatidylcholine constitutes 20% of the total phospholipids in chicken egg. At sn-1 and sn-2 positions it has palmitic acid (16:0) and oleic acid (18:1), respectively.[1]

Application

Egg PC has been used:
  • in the preparation of unilamellar vesicles[2]
  • in liposome preparation for proteoliposome reconstitution[3]
  • as a liposome component in lipid transfer assay[4]

Biochem/physiol Actions

Egg PC (phosphatidylcholine) in its saturated form favors inhibition of cholesterol absorption.[1] It also serves as a substrate for microbes for the synthesis of trimethylamine N-oxide (TMAO) thereby contributing to cardiovascular disease (CVD) risk.[1] It is used in lipid preparation[5] and liposomes for biophysical studies.[6]

Packaging

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap; Argon Filled Foil Pouch (840051C-1g)
5 mL Clear Glass Sealed Ampule; Argon Filled Foil Pouch (840051C-200mg)
5 mL Clear Glass Sealed Ampule; Argon Filled Foil Pouch (840051C-25mg)
5 mL Clear Glass Sealed Ampule; Argon Filled Foil Pouch (840051C-500mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

Classe de armazenamento

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Characterization of interactions of eggPC lipid structures with different biomolecules
Chahar FC, et al.
Chemistry and Physics of Lipids, 210(4), 60-69 (2018)
Christina M Bailey et al.
Langmuir : the ACS journal of surfaces and colloids, 33(43), 11986-11997 (2017-09-28)
Supported lipid bilayers (SLBs) have been used extensively in a variety of biotechnology applications and fundamental studies exploring lipid behavior. Despite their widespread use, various physicochemical parameters have yet to be thoroughly investigated for their impact on SLB formation. In
Using optical trap to measure the refractive index of a single animal virus in culture fluid with high precision
Pang Y, et al.
Biomedical Optics Express, 7(5), 1672-1689 (2016)
Structure-function insights into direct lipid transfer between membranes by Mmm1-Mdm12 of ERMES
Kawano S, et al.
The Journal of Cell Biology, 217(3), 959-974 (2018)
Roman Y Pishchalnikov et al.
Physical chemistry chemical physics : PCCP, 21(46), 25707-25719 (2019-11-14)
To prevent irreversible damage caused by an excess of incident light, the photosynthetic machinery of many cyanobacteria uniquely utilizes the water-soluble orange carotenoid protein (OCP) containing a single keto-carotenoid molecule. This molecule is non-covalently embedded into the two OCP domains

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