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Merck

850335P

Avanti

12:0 PC (DLPC)

Avanti Research - A Croda Brand

Sinônimo(s):

1,2-didodecanoyl-sn-glycero-3-phosphocholine; DLPC; PC(12:0/12:0)

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Sobre este item

Fórmula empírica (Notação de Hill):
C32H64NO8P
Número CAS:
Peso molecular:
621.83
MDL number:
UNSPSC Code:
51191904
NACRES:
NA.25

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SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCC)=O)COC(CCCCCCCCCCC)=O)=O

InChI

1S/C32H64NO8P/c1-6-8-10-12-14-16-18-20-22-24-31(34)38-28-30(29-40-42(36,37)39-27-26-33(3,4)5)41-32(35)25-23-21-19-17-15-13-11-9-7-2/h30H,6-29H2,1-5H3/t30-/m0/s1

InChI key

IJFVSSZAOYLHEE-PMERELPUSA-N

description

1,2-dilauroyl-sn-glycero-3-phosphocholine

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 g (850335P-1g), pkg of 1 × 200 mg (850335P-200mg), pkg of 1 × 25 mg (850335P-25mg), pkg of 1 × 500 mg (850335P-500mg)

manufacturer/tradename

Avanti Research - A Croda Brand

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

General description

Phosphatidylcholine (PC) is a strong bilayer-forming lipid. It the most common phospholipid in mammalian membranes.[1] It is also an important component of the mucosal layer of the colon.[2]
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

12:0 PC (DLPC) is suitable to use as a phospholipid (PL) standard to quantify phosphatidylcholine (PC) by electrospray ionization mass spectrometry (ESI-MS).[3]

Biochem/physiol Actions

Phosphatidylcholine (PC) functions as a surfactant within the mucus to form a hydrophobic surface to inhibit bacterial penetrance.[2] It is used to treat fat embolism. Phosphatidylcholine lowers the levels of cholesterol and triglycerides.[4]

Packaging

20 mL Clear Glass Screw Cap Vial (850335P-1g)
20 mL Clear Glass Screw Cap Vial (850335P-500mg)
5 mL Amber Glass Screw Cap Vial (850335P-200mg)
5 mL Amber Glass Screw Cap Vial (850335P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Classe de armazenamento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Integrative Medicine - E-Book (2017)
The Membranes of Cells (2016)
Nhiem Tran et al.
The journal of physical chemistry letters, 9(12), 3397-3402 (2018-05-29)
The transition between the lyotropic liquid crystalline lamellar and the bicontinuous cubic mesophase drives multiple fundamental cellular processes involving changes in cell membrane topology, including endocytosis and membrane budding. While several theoretical models have been proposed to explain this dynamic
Extraction and profiling of plant polar glycerol lipids
Liu Y and Wang X
Bio-protocol (2016)
John P Kowalski et al.
Chemical research in toxicology, 32(12), 2488-2498 (2019-12-05)
Cytochrome P450 4B1 (CYP4B1) has been explored as a candidate enzyme in suicide gene systems for its ability to bioactivate the natural product 4-ipomeanol (IPO) to a reactive species that causes cytotoxicity. However, metabolic limitations of IPO necessitate discovery of

Artigos

The critical micelle concentration (CMC) can be approximately defined as the lipid monomer concentration at which appreciable amounts (>5% of total) of micellar aggregates first begin to appear in the equilibrium: nM1<=>Mn

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