850365P

18:0 PC (DSPC)

Avanti Research^™ - A Croda Brand

• Sinônimo(s): 1,2-dioctadecanoyl-sn-glycero-3-phosphocholine; DSPC; PC(18:0/18:0)
• Fórmula empírica (Notação de Hill): C₄₄H₈₈NO₈P
• Número CAS: 816-94-4
• Peso molecular: 790.15
• Código UNSPSC: 51191904
• NACRES: NA.25

Propriedades

• descrição: 1,2-distearoyl-sn-glycero-3-phosphocholine
• Ensaio: >99% (TLC)
• forma: powder
• embalagem: pkg of 1 × 1 g (850365P-1G); pkg of 1 × 200 mg (850365P-200MG); pkg of 1 × 25 mg (850365P-25MG); pkg of 1 × 500 mg (850365P-500MG)
• fabricante/nome comercial: Avanti Research^™ - A Croda Brand
• aplicação(ões): advanced drug delivery
• tipo de lipídio: phospholipids; cardiolipins
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O)=O
• InChI: 1S/C44H88NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h42H,6-41H2,1-5H3/t42-/m1/s1
• chave InChI: NRJAVPSFFCBXDT-HUESYALOSA-N

Descrição

Descrição geral

1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC) is a phospholtidylcholine with alkyl chain comprising 18 carbons. It has phophatidylcholine head group and its structure is similar to 1,2-dipalmitoyl-sn-glycero-3-phosphatidylcholine (DPPC).

The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Aplicação

18:0 PC (DSPC) has been used:

• in the microbubble monolayer preparation for biomolecule delivery studies into protoplasts
• in the preparation of liposomes for immobilization studies
• in the generation of porphyrin-phospholipid (PoP) liposomes for irinotecan (IRT) and doxorubicin delivery

Ações bioquímicas/fisiológicas

1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC) is used in combination with other members of phosphatidylcholine for the generation of mixed bilayer system. It is majorly used in conventional and stealth liposome preparation for drug delivery studies.

Embalagem

20 mL Clear Glass Screw Cap Vial (850365P-1G)

20 mL Clear Glass Screw Cap Vial (850365P-500MG)

5 mL Amber Glass Screw Cap Vial (850365P-200MG)

5 mL Amber Glass Screw Cap Vial (850365P-25MG)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable