MABN18

Anti-PINK1 Antibody, clone N4/49

clone N4/49, from mouse

• Synonym(s): PTEN induced putative kinase 1, protein kinase BRPK, serine/threonine-protein kinase PINK1, PTEN-induced putative kinase protein 1, Parkinson disease (autosomal recessive) 6
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• fonte biológica: mouse
• Nível de qualidade: 100
• forma do anticorpo: purified immunoglobulin
• antibody product type: primary antibodies
• clone: N4/49, monoclonal
• species reactivity: human
• technique(s): immunohistochemistry: suitable; western blot: suitable
• Isotipo: IgG1κ
• nº de adesão NCBI: NP_115785
• nº de adesão UniProt: Q9BXM7
• enviado em: wet ice
• Gene Information: human ... PINK1(65018)

Description

Descrição geral

Mutations in the PTEN-induced kinase 1 (PINK1) gene located within the PARK6 locus on chromosome 1p35-p36 have recently been identified in patients with recessive early-onset Parkinson disease. Data suggests that PINK1 may be the second most common causative gene next to parkin in parkinsonism with the recessive mode of inheritance.

Especificidade

This antibody recognizes PINK1.

Aplicação

This Anti-PINK1 Antibody, clone N4/49 is validated for use in IH, WB for the detection of PINK1.

Western Blot Analysis: A previous lot of MABN18 recognized PINK1 in HEK cells and a rat brain LSP, as reported by an independent laboratory (UC Davis/NIH NeuroMab Facility; www.neuromab.org/neuromab@ucdavis.edu).

Qualidade

Evaluated by Immunohistochemistry in human normal brain tissue.

Immunohistochemistry Analysis: A 1:500 dilution of this antibody detected PINK1 in human normal brain tissue.

Descrição-alvo

63 kDa Observed

forma física

Format: Purified

Nota de análise

Control
Human normal brain tissue

Outras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Safety Information

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• WGK: WGK 1
• Ponto de fulgor (ºF): Not applicable
• Ponto de fulgor (ºC): Not applicable