MATPAM3CSK4

PAM3CSK4 Non-Endotoxin Pyrogen (NEP) Control

for use with PyroMAT^®

• Synonym(s): Lipopeptide, Triacylated Lipopeptide

Properties

• Agency: EP; JP 4.06; USP
• Nível de qualidade: 400
• forma: lyophilized
• application(s): pharmaceutical; pyrogen testing
• compatibilidade: for use with PyroMAT^®
• enviado em: ambient
• temperatura de armazenamento: 2-8°C
• adequação: pyrogenic bacteria

Description

Descrição geral

PAM3CSK4 is a non-endotoxin pyrogen which will serve as a positive control during pyrogen testing with PyroMAT^® system. Non- Endotoxin Pyrogen (NEP) Control PAM3CSK4 is a synthetic synthetic triacylated lipopeptide, supplied in a lyophilized form. PAM3CSK4 Non- Endotoxin Pyrogen (NEP) Control activates TLR1/TLR2 receptor of monocytes and is used as a positive control for PyroMAT^® system. The response to pyrogenic substances is determined by measuring the Interleukin-6 (IL-6) produced by the monocytes using ELISA microplate.

Aplicação

PAM3CSK4 control can be used as a positive control with the PyroMAT^® System. It is to be used for Product Specific Validation (PSV) and routine testing to show that the system can detect non-endotoxin pyrogen contaminants in pharmaceutical products.

Informações legais

PYROMAT is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Código de classe de armazenamento: 11 - Combustible Solids
• WGK: WGK 3
• Ponto de fulgor (ºF): Not applicable
• Ponto de fulgor (ºC): Not applicable