Merck
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NADPH-RO

Roche

NADPH

powder, =97% (dry weight)

Synonym(s):
β-Nicotinamide adenine dinucleotide 2′-phosphate reduced tetrasodium salt hydrate, β-NADPH, 2′-NADPH hydrate, Coenzyme II reduced tetrasodium salt, Dihydronicotinamide adenine dinucleotide phosphate tetrasodium salt, NADPH Na4, TPNH2 Na4, Triphosphopyridine nucleotide reduced tetrasodium salt
Empirical Formula (Hill Notation):
C21H26N7Na4O17P3 · xH2O
CAS Number:
Molecular Weight:
833.35 (anhydrous basis)
Número MDL:
ID de substância PubChem:

descrição

Tetrasodium salt

Nível de qualidade

100

teor

=97% (dry weight)

forma

powder

embalagem

pkg of 1 g (10621706001)
pkg of 100 mg (10107824001)
pkg of 500 mg (10621692001)

manufacturer/tradename

Roche

λmax

260 and 340 nm

enviado em

wet ice

temperatura de armazenamento

2-8°C

SMILES string

[Na+].[Na+].[Na+].[Na+].NC(=O)C1=CN(C=CC1)[C@H]2O[C@@H](COP([O-])(=O)OP([O-])(=O)OC[C@H]3O[C@H]([C@H](OP([O-])([O-])=O)[C@@H]3O)n4cnc5c(N)ncnc45)[C@H](O)[C@@H]2O

InChI

1S/C21H30N7O17P3.4Na/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32;;;;/h1,3-4,7-8,10-11,13-16,20-21,29-31H,2,5-6H2,(H2,23,32)(H,36,37)(H,38,39)(H2,22,24,25)(H2,33,34,35);;;;/q;4*+1/p-4/t10-,11+,13-,14+,15-,16+,20-,21+;;;;/m0..../s1

InChI key

WYWWVJHQDVCHKF-MPUNMZHWSA-J

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Descrição geral

  • Absorbance coefficients: 15.0 x 103 l x mol-1 x cm-1 at 260 nm, 6.3 x 103 l x mol-1 x cm-1 at 340 nm
  • Absorbance maxima: 260 nm and 340 nm
  • Molecular weight: NADPH-Na4: Mr = 833.4, NADPH: Mr = 745.4
  • pH value in water: 8.0 ± 1.0 (10 mg/ml)
Amorphous powder bottled under nitrogen.

Aplicação

NADPH-RO has been used for the determination of thioredoxin reductase activity.[1]

Ações bioquímicas/fisiológicas

NADPH is an electron donor and a cofactor for many redox enzymes including nitric oxide synthetase.

Qualidade

  • Purity: =97% ß-NADPH-Na4 based on dry weight (enzymatically and absorbance at 340 nm), =80% (absorbance at 260 nm)
  • Organic solvents: =3% (GC)

Nota de preparo

Storage conditions (working solution): 2 to 8 °C
10 mg/ml in Na-bicarbonate buffer, pH 9, contains at least 95% NADPH after 4 weeks at 2 to 8 °C.

Nota de análise

Absorbance coefficients: 15.0 x 103 l x mol-1 x cm-1 at 260 nm, 6.3 x 103 l x mol-1 x cm-1 at 340 nm

Outras notas

For life science research only. Not for use in diagnostic procedures.
Packaged based on solid weight.

Código de classe de armazenamento

11 - Combustible Solids

WGK

WGK 1

Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Certificate of Analysis

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Certificate of Origin

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