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(±)-Catechin hydrate

primary reference standard

trans-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol, trans-3,3′,4′,5,7-Pentahydroxyflavane
Empirical Formula (Hill Notation):
C15H14O6 · xH2O
Número CAS:
Peso molecular:
290.27 (anhydrous basis)
Número EC:
Número MDL:
ID de substância PubChem:


primary reference standard





prazo de validade

limited shelf life, expiry date on the label




food and beverages

temperatura de armazenamento


SMILES string




InChI key


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Descrição geral

Catechin hydrate, a flavononol, belongs to the class of flavonoids. It is present in abundance in Siberian larch (Larix sibirica) and in silymarin extract of milk thistle seeds. Its potent chemopreventive action by virtue of the regulation of genes through the ARE-dependent pathway has been widely investigated. It also shows potential antioxidant activity against ovarian cancer cell growth, cellular melanogenesis, human breast cancer, etc.
Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.


Catechin hydrate may be used as a reference standard for the determination of the analyte in walnut leaves by high-performance liquid chromatography (HPLC).

Ações bioquímicas/fisiológicas

Polyphenolic antioxidant. Used in traditional Chinese medicine.


Exclamation mark

Palavra indicadora


Frases de perigo

Classificações de perigo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3


Respiratory system

Código de classe de armazenamento

11 - Combustible Solids



Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Certificado de análise

Certificado de origem

HPLC determination of phenolic acids, flavonoids and juglone in walnut leaves
Nour V, et al.
Journal of Chromatographic Science, 51(9) (2013)
Stéphane Bastianetto et al.
CNS neuroscience & therapeutics, 15(1), 76-83 (2009-02-21)
Various studies have reported on the neuroprotective effects of polyphenols, widely present in food, beverages, and natural products. For example, we have shown that resveratrol, a polyphenol enriched in red wine and other foods such as peanuts, protects hippocampal cells
Electrochemical, thermodynamic and adsorption studies of (+)-catechin hydrate as natural mild steel corrosion inhibitor in 1 M HCl
Hussin MH and Kassim MJ
International Journal of Electrochemical Science, 6(5), 1396-1414 (2011)
Silvia Mandel et al.
Free radical biology & medicine, 37(3), 304-317 (2004-06-30)
Neurodegeneration in Parkinson's, Alzheimer's, and other neurodegenerative diseases seems to be multifactorial, in that a complex set of toxic reactions including inflammation, glutamatergic neurotoxicity, increases in iron and nitric oxide, depletion of endogenous antioxidants, reduced expression of trophic factors, dysfunction
R Hursel et al.
Obesity reviews : an official journal of the International Association for the Study of Obesity, 12(7), e573-e581 (2011-03-04)
Different outcomes of the effect of catechin-caffeine mixtures and caffeine-only supplementation on energy expenditure and fat oxidation have been reported in short-term studies. Therefore, a meta-analysis was conducted to elucidate whether catechin-caffeine mixtures and caffeine-only supplementation indeed increase thermogenesis and

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