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04238

Sigma-Aldrich

Hydroxyapatite

puriss., meets analytical specification of Ph. Eur., BP, FCC, E341, ≥90% (calculated on glowed substance)

Sinônimo(s):
Durapatite, Hydroxylapatite, Calcium phosphate hydroxide
Fórmula linear:
3Ca3(PO4)2 · Ca(OH)2
Número CAS:
Peso molecular:
502.31
Número EC:
Número MDL:
ID de substância PubChem:
NACRES:
NA.21

grau

puriss.

Nível de qualidade

200

teor

≥90% (calculated on glowed substance)
35-40% Ca basis

forma

powder

qualidade

meets analytical specification of Ph. Eur., BP, FCC, E341

Impurezas

residual solvents, complies
≤0.001% heavy metals (as Pb)
≤0.2% insoluble in HCl

perda

≤8% loss on ignition, 800 °C

traços de ânion

chloride (Cl-): ≤1500 mg/kg
fluoride (F-): ≤50 mg/kg
sulfate (SO42-): ≤5000 mg/kg

traços de cátion

As: ≤2 mg/kg
Cd: ≤1 mg/kg
Cu: ≤20 mg/kg
Fe: ≤400 mg/kg
Hg: ≤1 mg/kg
Pb: ≤2 mg/kg
Zn: ≤20 mg/kg

SMILES string

[Ca++].[Ca++].[Ca++].[Ca++].O[Ca+].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O

InChI

1S/5Ca.3H3O4P.H2O/c;;;;;3*1-5(2,3)4;/h;;;;;3*(H3,1,2,3,4);1H2/q5*+2;;;;/p-10

InChI key

XYJRXVWERLGGKC-UHFFFAOYSA-D

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Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Certificado de análise

Certificado de origem

P Ducheyne et al.
Biomaterials, 7(2), 97-103 (1986-03-01)
Hydroxyapatite from two sources was electrophoretically deposited onto flat titanium plate material. Depending upon the deposition conditions various changes in the structure of the ceramic were identified. A well-adhering Ti-P compound was present at the interface. Hydroxyapatite oxygenated to various...
Mechanical properties of sintered hydroxyapatite for prosthetic applications.
Akao M ,et al.
J. Mater. Sci., 16(3), 809-812 (1981)
Chemical characterization of silicon-substituted hydroxyapatite
Gibson I, et al.
Journal of Biomedical Materials Research, 44(4), 422-428 (1999)
D Mata et al.
Journal of biomedical nanotechnology, 10(5), 725-743 (2014-04-17)
Biomaterials can still be reinvented to become simple and universal bone regeneration solutions. Following this roadmap, a bone graft of carbon nanotube (CNT)/glass/hydroxyapatite (HA) with controlled CNT agglomeration state was designed with multifunctionalities able to stimulate the bone cell phenotype....
Sergio Bertazzo et al.
Nature materials, 12(6), 576-583 (2013-04-23)
The accumulation of calcified material in cardiovascular tissue is thought to involve cytochemical, extracellular matrix and systemic signals; however, its precise composition and nanoscale architecture remain largely unexplored. Using nano-analytical electron microscopy techniques, we examined valves, aortae and coronary arteries...

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