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16033

Sigma-Aldrich

1,2-Propanediol

meets analytical specification of Ph. Eur., BP, USP, ≥99.5%

Sinônimo(s):
1,2-PDO, Propylene glycol
Fórmula linear:
CH3CH(OH)CH2OH
Número CAS:
Peso molecular:
76.09
Beilstein:
1340498
Número EC:
Número MDL:
ID de substância PubChem:
NACRES:
NA.21

densidade de vapor

2.62 (vs air)

Nível de qualidade

200

pressão de vapor

0.08 mmHg ( 20 °C)

teor

≥99.5%

forma

liquid

temperatura de autoignição

779 °F

qualidade

meets analytical specification of Ph. Eur., BP, USP

prazo de validade

24 mo.

Lim. expl.

12.5 %

Impurezas

acidic reac. impurities, complies
organic volatile impurities, complies (GC)
oxidizing substances, complies
reducing matter, complies
residual solvents, complies
≤0.0005% heavy metals (as Pb)
≤0.002% free alkali (as NaOH)
≤0.003% free acid (as CH3COOH)
≤0.2% water (Karl Fischer)

resíduo de ignição

≤0.005% (as SO4)

índice de refração

n20/D 1.431-1.433
n20/D 1.432 (lit.)

pb

187 °C (lit.)

pf

−60 °C (lit.)

densidade

1.036 g/mL at 25 °C (lit.)

traços de ânion

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤50 mg/kg

adequação

complies for appearance of solution

SMILES string

CC(O)CO

InChI

1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3

InChI key

DNIAPMSPPWPWGF-UHFFFAOYSA-N

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Descrição geral

1,2-Propanediol is an important petrochemical that can be prepared by the hydrogenolysis of glycerol. It is mainly used as a cryoprotectant for biological samples and also as an additive in food, cosmetic and pharmaceutical industries.
1,2-Propanediol is an 1,2-alkanediol. It can be obtained from glycerol, via hydrogenolysis in the presence of Ru/C and Amberlyst ion-exchange resins.

Aplicação

1,2-Propanediol may be employed as a cryoprotective agent for the preservation (by cooling to sub-zero temperatures) of human embryos and and oocytes (human and mouse).

Embalagem

bottled under inert gas

Outras notas

The article number 16033-4X5L will be discontinued. Please order the single bottle 16033-5L which is physically identical with the same exact specifications.
The article number 16033-6X1L will be discontinued. Please order the single bottle 16033-1L which is physically identical with the same exact specifications.
The article number 16303-4X2.5L-R will be discontinued. Please order the single bottle 16303-2.5L-R which is physically identical with the same exact specifications.

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Ponto de fulgor (ºF)

219.2 °F - closed cup

Ponto de fulgor (ºC)

104 °C - closed cup

Equipamento de proteção individual

Eyeshields, Gloves

Certificado de análise

Certificado de origem

Aqueous phase hydrogenolysis of glycerol to 1, 2-propanediol without external hydrogen addition.
Roy D, et al.
Catalysis Today, 156(1), 31-37 (2010)
Glycerol hydrogenolysis to 1, 2-propanediol catalyzed by a heat-resistant ion-exchange resin combined with Ru/C.
Miyazawa T, et al.
Applied Catalysis A: General, 329, 30-35 (2007)
B Lassalle et al.
Fertility and sterility, 44(5), 645-651 (1985-11-01)
Eighty-five human embryos fertilized in vitro were frozen and thawed with 1,2 propanediol as a cryoprotective agent. The effects of viability of in vitro culture duration, stage, and morphologic appearance of embryos were examined after thawing. Survival was higher for...
Yusha Imtiaz et al.
Nanomaterials (Basel, Switzerland), 10(8) (2020-08-23)
Polysaccharides have been shown to have immunomodulatory properties. Modulation of the immune system plays a crucial role in physiological processes as well as in the treatment and/or prevention of autoimmune and infectious diseases. Cellulose nanocrystals (CNCs) are derived from cellulose...
Mohammad Chand Ali et al.
Talanta, 203, 16-22 (2019-06-17)
The efficient extraction of natural products from biomass is deemed an essential area of interest using green technology in the pharmaceutical and biochemical industries. In recent years, deep eutectic solvents (DESs) have been paying broad interest as compatible, safe, and...

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