Merck
Todas as fotos(3)

410225

Sigma-Aldrich

Glycine

ACS reagent, ≥98.5%

Sinônimo(s):
Aminoacetic acid, Aminoethanoic acid, Glycocoll
Fórmula linear:
NH2CH2COOH
Número CAS:
Peso molecular:
75.07
Beilstein:
635782
Número EC:
Número MDL:
eCl@ss:
32160406
ID de substância PubChem:
NACRES:
NA.21

Nível de qualidade

200

grau

ACS reagent

teor

≥98.5%

forma

crystals
powder or granules

Impurezas

H2SO4, passes test (darkened)
Hydrolyzable subsances, passes test

resíduo de ignição

≤0.1%

pKa (25 °C)

(1) 2.35, (2) 9.60
2.35

pf

240 °C (dec.) (lit.)

traços de ânion

chloride (Cl-): ≤0.005%
sulfate (SO42-): ≤0.005%

traços de cátion

NH4+: ≤0.005%
heavy metals: ≤0.002% (by ICP)

application(s)

peptide synthesis

SMILES string

NCC(O)=O

InChI

1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

InChI key

DHMQDGOQFOQNFH-UHFFFAOYSA-N

Gene Information

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Aplicação

Glycine has been used in whole-cell patch clamp recording to measure inward NMDA (N-methyl-D-aspartate) currents. It has also been used as a model organic system in crystallography to demonstrate a novel acoustic nebulization platform.

Embalagem

50, 250 g in poly bottle

Ações bioquímicas/fisiológicas

Glycine is a non-essential amino acid. Influx of calcium through the cell membrane is mediated by glycine-gated channel. Glycine participates in the synthesis of porphyrins, purine and serine. It also serves as a competitive agonist for glutamate in binding to the NMDA (N-methyl-D-aspartate) receptors. Glycine synthesis might be increased in rapidly proliferating cancer cells, due to increased demand for the amino acid.
Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

Código de classe de armazenamento

11 - Combustible Solids

WGK

WGK 1

Ponto de fulgor (ºF)

Not applicable

Ponto de fulgor (ºC)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificado de análise

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Certificado de origem

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Controversial Effects of D-Amino Acid Oxidase Activator (DAOA)/G72 on D-Amino Acid Oxidase (DAO) Activity in Human Neuronal, Astrocyte and Kidney Cell Lines: The N-methyl D-aspartate (NMDA) Receptor Hypofunction Point of View
Vinita Jagannath
Frontiers in Molecular Neuroscience (2017)
A Novel Acoustomicrofluidic Nebulization Technique Yielding New Crystallization Morphologies
Heba Ahmed
Advanced Materials, 30(3) (2018)
Amino acids: metabolism, functions, and nutrition
Guoyao Wu
Amino Acids, 37(1), 1-17 (2009)
Metabolite Profiling Identifies a Key Role for Glycine in Rapid Cancer Cell Proliferation
Mohit Jain
Science, 336(6084), 1040-1044 (2012)
Amino acids: metabolism, functions, and nutrition.
Wu G
Amino Acids, 37(1), 1-17 (2009)

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