410225

Glycine

ACS reagent, ≥98.5%

• Sinônimo(s): Aminoacetic acid, Aminoethanoic acid, Glycocoll
• Fórmula linear: NH₂CH₂COOH
• Número CAS: 56-40-6
• Peso molecular: 75.07
• Beilstein: 635782
• Número EC: 200-272-2
• Número MDL: MFCD00008131
• eCl@ss: 32160406
• ID de substância PubChem: 24865701
• NACRES: NA.21

Propriedades

• Nível de qualidade: 200
• grau: ACS reagent
• teor: ≥98.5%
• forma: crystals; powder or granules
• Impurezas: H₂SO₄, passes test (darkened); Hydrolyzable subsances, passes test
• resíduo de ignição: ≤0.1%
• pKa (25 °C): (1) 2.35, (2) 9.60; 2.35
• pf: 240 °C (dec.) (lit.)
• traços de ânion: chloride (Cl^-): ≤0.005%; sulfate (SO₄^2-): ≤0.005%
• traços de cátion: NH₄⁺: ≤0.005%; heavy metals: ≤0.002% (by ICP)
• application(s): peptide synthesis
• SMILES string: NCC(O)=O
• InChI: 1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
• InChI key: DHMQDGOQFOQNFH-UHFFFAOYSA-N
• Gene Information: rat ... Grin2a(24409)

Descrição

Aplicação

Glycine has been used in whole-cell patch clamp recording to measure inward NMDA (N-methyl-D-aspartate) currents. It has also been used as a model organic system in crystallography to demonstrate a novel acoustic nebulization platform.

Embalagem

50, 250 g in poly bottle

Ações bioquímicas/fisiológicas

Glycine is a non-essential amino acid. Influx of calcium through the cell membrane is mediated by glycine-gated channel. Glycine participates in the synthesis of porphyrins, purine and serine. It also serves as a competitive agonist for glutamate in binding to the NMDA (N-methyl-D-aspartate) receptors. Glycine synthesis might be increased in rapidly proliferating cancer cells, due to increased demand for the amino acid.

Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• WGK: WGK 1
• Ponto de fulgor (ºF): Not applicable
• Ponto de fulgor (ºC): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)