Merck
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47673

Sigma-Aldrich

Formaldehyde solution

tested according to Ph. Eur.

Sinônimo(s):
Formalin, Formaldehydi solutio 35 per centum
Fórmula linear:
HCHO
Número CAS:
Peso molecular:
30.03
Beilstein:
1209228
Número MDL:
ID de substância PubChem:
NACRES:
NA.25

Nível de qualidade

200

Agency

USP/NF
tested according to Ph. Eur.

densidade de vapor

1.03 (vs air)

pressão de vapor

52 mmHg ( 37 °C)

forma

liquid

temperatura de autoignição

572 °F

contém

9.0-15.0 % (v/v) methanol as stabilizer

concentração

25-50%

solubilidade

water: soluble

densidade

1.09 g/mL at 25 °C (lit.)

adequação

suitable for manufacturing use (Laboratory chemicals)

SMILES string

[H]C([H])=O

InChI

1S/CH2O/c1-2/h1H2

InChI key

WSFSSNUMVMOOMR-UHFFFAOYSA-N

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Aplicação

Formaldehyde solution has been used to fix labeled cells during flow cytometry.

Ações bioquímicas/fisiológicas

Formaldehyde is the simplest aldehyde that denatures the bihelical regions of RNA and converts the polynucleotides into random coils. It is a genotoxic substance that significantly induces DNA-protein crosslinks (DPC), sister-chromatid exchanges, micronuclei formation and leads to cytotoxicity. It also induces tumors in the nasal epithelium of rats and supposed to be a human carcinogen.

Atenção

may become turbid on storage

Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Carc. 1B - Eye Dam. 1 - Flam. Liq. 3 - Muta. 2 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 1 - STOT SE 3

Órgãos-alvo

Respiratory system

Código de classe de armazenamento

3 - Flammable liquids

WGK

WGK 3

Ponto de fulgor (ºF)

133.0 °F - closed cup

Ponto de fulgor (ºC)

56.11 °C - closed cup

Equipamento de proteção individual

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Certificado de análise

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Certificado de origem

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Mais documentos

Cotações e pedidos

J L Wilson et al.
Journal of immunology (Baltimore, Md. : 1950), 163(12), 6365-6370 (1999-12-10)
NK cells have the capacity to spontaneously kill tumor cell lines, in particular cell lines of hemopoietic origin. In contrast, they do not generally kill nontransformed autologous cells. However, here we demonstrate that short-term activated polyclonal human NK cells, as
Dependence of the sedimentation coefficient on molecular weight of RNA after reaction with formaldehyde.
H Boedtker
Journal of molecular biology, 35(1), 61-70 (1968-07-14)
O Merk et al.
Environmental and molecular mutagenesis, 32(3), 260-268 (1998-11-14)
Formaldehyde (FA) is a genotoxic substance, induces tumors in the nasal epithelium of rats, and is suspected to be a human carcinogen. As a primary DNA lesion, FA induces DNA-protein crosslinks (DPC) and the formation of DPC has been used
Cindy S Ma et al.
The Journal of experimental medicine, 205(7), 1551-1557 (2008-07-02)
Hyper-immunoglobulin E syndrome (HIES) is a primary immune deficiency characterized by abnormal and devastating susceptibility to a narrow spectrum of infections, most commonly Staphylococcus aureus and Candida albicans. Recent investigations have identified mutations in STAT3 in the majority of HIES
G R Moore et al.
Neurology, 55(10), 1506-1510 (2000-11-30)
To determine the pathologic basis of areas not exhibiting signal of the short-T2 component of the T2 relaxation distribution in MS, as studied in formalin-fixed brain. A myelin-specific MRI signal would be of great importance in assessing demyelination in patients

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