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47673

Sigma-Aldrich

Formaldeído

tested according to Ph. Eur.

Sinônimo(s):

Formalina

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About This Item

Fórmula linear:
HCHO
Número CAS:
Peso molecular:
30.03
Beilstein:
1209228
Número MDL:
Código UNSPSC:
12352114
ID de substância PubChem:
NACRES:
NA.25

Agency

USP/NF
tested according to Ph. Eur.

Nível de qualidade

densidade de vapor

1.03 (vs air)

pressão de vapor

52 mmHg ( 37 °C)

forma

liquid

temperatura de autoignição

572 °F

contém

9.0-15.0 % (v/v) methanol as stabilizer

concentração

25-50%

solubilidade

water: soluble

densidade

1.09 g/mL at 25 °C (lit.)

adequação

suitable for manufacturing use (Laboratory chemicals)

cadeia de caracteres SMILES

[H]C([H])=O

InChI

1S/CH2O/c1-2/h1H2

chave InChI

WSFSSNUMVMOOMR-UHFFFAOYSA-N

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Aplicação

Formaldehyde solution has been used to fix labeled cells during flow cytometry.

Ações bioquímicas/fisiológicas

Formaldehyde is the simplest aldehyde that denatures the bihelical regions of RNA and converts the polynucleotides into random coils. It is a genotoxic substance that significantly induces DNA-protein crosslinks (DPC), sister-chromatid exchanges, micronuclei formation and leads to cytotoxicity. It also induces tumors in the nasal epithelium of rats and supposed to be a human carcinogen.

Atenção

may become turbid on storage

Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Carc. 1B - Eye Dam. 1 - Flam. Liq. 3 - Muta. 2 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 1 - STOT SE 3

Órgãos-alvo

Eyes,Central nervous system, Respiratory system

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

133.0 °F

Ponto de fulgor (°C)

56.11 °C

Equipamento de proteção individual

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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Environmental and molecular mutagenesis, 32(3), 260-268 (1998-11-14)
Formaldehyde (FA) is a genotoxic substance, induces tumors in the nasal epithelium of rats, and is suspected to be a human carcinogen. As a primary DNA lesion, FA induces DNA-protein crosslinks (DPC) and the formation of DPC has been used
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