50202

Supelco

Tetrahydrocurcumin

analytical standard

Sinônimo(s):
1,7-Bis(4-hydroxy-3-methoxyphenyl)-3,5-heptanedione
Empirical Formula (Hill Notation):
C21H24O6
Número CAS:
Peso molecular:
372.41
Beilstein/REAXYS Number:
3485469
Número MDL:
ID de substância PubChem:
NACRES:
NA.24

grau

analytical standard

Nível de qualidade

100

teor

≥95.0% (HPLC)

forma

neat

prazo de validade

limited shelf life, expiry date on the label

aplicação(ões)

HPLC: suitable
gas chromatography (GC): suitable

Setor em destaque

Food and Beverages

formato

neat

SMILES string

COc1cc(CCC(=O)CC(=O)CCc2ccc(O)c(OC)c2)ccc1O

InChI

1S/C21H24O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h5-6,9-12,24-25H,3-4,7-8,13H2,1-2H3

InChI key

LBTVHXHERHESKG-UHFFFAOYSA-N

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Descrição geral

Tetrahydrocurcumin is a colorless compound and a major metabolite of curcumin, which is known to possess antioxidant activity and inhibitory effects on tertiary butyl hydroperoxide-induced lipid peroxidation. It can be obtained via hydrogenation of curcumin in the presence of platinum(IV)oxide.

Aplicação

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Embalagem

Bottomless glass bottle. Contents are inside inserted fused cone.

RIDADR

NONH for all modes of transport

WGK Alemanha

WGK 3

Ponto de fulgor (ºF)

385.2 °F

Ponto de fulgor (ºC)

196.2 °C

Certificado de análise
Certificado de origem
Protective role of tetrahydrocurcumin against erythromycin estolate-induced hepatotoxicity
Pari L and Murugan P
Pharmacological Research, 49, 481-486 (2004)
Saipin Setthacheewakul et al.
AAPS PharmSciTech, 12(1), 152-164 (2010-12-25)
The objectives of this study were to develop and evaluate a novel self-emulsifying floating drug delivery system (SEFDDS) that resulted in improved solubility, dissolution, and controlled release of the poorly water-soluble tetrahydrocurcumin (THC). The formulations of liquid self-emulsifying drug delivery...
Namfa Sermkaew et al.
AAPS PharmSciTech, 14(1), 321-331 (2013-01-16)
Novel self-microemulsifying floating tablets were developed to enhance the dissolution and oral absorption of the poorly water-soluble tetrahydrocurcumin (THC). Their physicochemical properties and THC permeability across Caco-2 cell monolayers were assessed. The self-microemulsifying liquid containing THC was adsorbed onto colloidal...
Leelavinothan Pari et al.
Molecular and cellular biochemistry, 341(1-2), 109-117 (2010-03-27)
The present study evaluates the combined effect of tetrahydrocurcumin and chlorogenic acid on oxidative stress in streptozotocin-nicotinamide-induced diabetic rats. Rats were rendered diabetic by a single intraperitoneal injection (i.p) of streptozotocin (45 mg/kg BW), 15 min after an i.p injection...
Li-Rong Shen et al.
BioFactors (Oxford, England), 39(1), 133-140 (2013-01-18)
Turmeric has been used commonly as a spice, food additive, and an herbal medicine worldwide. Known as a bioactive polyphenolic extract of Turmeric, curcumin has a broad range of health benefit properties for humans. Recently, active research on curcumin with...

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